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继发于 Guillain Mollaret 三角区海绵状血管瘤的肥厚性橄榄体变性：两例报告

Hypertrophic olivary degeneration secondary to a Guillain Mollaret triangle cavernoma: Two case report.

作者信息

Marrakchi Salma, Hsain Ihssan Hadj, Guelzim Yousra, Ech-Cherif Najwa El Kettani, Fikri Meriem, Jiddane Mohamed, Touarsa Firdaous

机构信息

Neuroradiology Department, Head and Neck Hospital of Rabat, Rabat, Morocco.

出版信息

Radiol Case Rep. 2024 Jun 5;19(8):3538-3544. doi: 10.1016/j.radcr.2024.04.078. eCollection 2024 Aug.

DOI:10.1016/j.radcr.2024.04.078
PMID:38948902
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11214340/
Abstract

Hypertrophic olivary degeneration (HOD) is a rare form of transsynaptic degeneration. It is caused by a damage at the Guillain-Mollaret triangle (GMT), which is defined by three anatomical structures: the dentate nucleus, the red nucleus, and the inferior olivary nucleus (ION). Clinically, it may be revealed by palatal myoclonus. On MRI, it appears as a unilateral or bilateral enlargement of the inferior olivary nucleus which shows a high signal intensity on T2-weighted images, with sometimes a cerebellar atrophy. Here we report 2 cases of healthy patients which present hemorrhagic brainstem cavernomas, complicated later by the development of palatal myoclonus and cerebellar ataxia, with MRI features corresponding to an (HOD) secondary to a (GMT) cavernoma. The purpose is to explain the mechanism of (HOD) subsequent to lesion in (GMT), and to describe magnetic resonance imaging features.

摘要

肥大性橄榄体变性（HOD）是一种罕见的跨突触变性形式。它由Guillain-Mollaret三角（GMT）损伤引起，该三角由三个解剖结构定义：齿状核、红核和下橄榄核（ION）。临床上，它可能表现为腭肌阵挛。在MRI上，它表现为下橄榄核单侧或双侧增大，在T2加权图像上呈高信号强度，有时伴有小脑萎缩。我们在此报告2例健康患者，他们患有出血性脑干海绵状血管瘤，随后并发腭肌阵挛和小脑共济失调，MRI特征符合继发于（GMT）海绵状血管瘤的（HOD）。目的是解释（GMT）病变后（HOD）的机制，并描述磁共振成像特征。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8d39/11214340/58c3759c9c6e/gr8.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8d39/11214340/344bcb391905/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8d39/11214340/a52a2b85b7bd/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8d39/11214340/cf46a0fba6a2/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8d39/11214340/41747c357140/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8d39/11214340/cb8a66a9a81a/gr5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8d39/11214340/0d0bda5d22f2/gr6.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8d39/11214340/617ad25d26ed/gr7.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8d39/11214340/58c3759c9c6e/gr8.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8d39/11214340/344bcb391905/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8d39/11214340/a52a2b85b7bd/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8d39/11214340/cf46a0fba6a2/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8d39/11214340/41747c357140/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8d39/11214340/cb8a66a9a81a/gr5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8d39/11214340/0d0bda5d22f2/gr6.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8d39/11214340/617ad25d26ed/gr7.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8d39/11214340/58c3759c9c6e/gr8.jpg

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Long-standing myoclonic hand tremor as an isolated symptom of hypertrophic olivary degeneration.长期存在的肌阵挛性手震颤作为肥厚性橄榄核变性的孤立症状。
Clin Neurol Neurosurg. 2023 Sep;232:107871. doi: 10.1016/j.clineuro.2023.107871. Epub 2023 Jul 3.
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Hypertrophic olivary degeneration: a description of four cases of and a literature analysis.肥厚性橄榄体变性：4例病例描述及文献分析
Quant Imaging Med Surg. 2022 Jun;12(6):3480-3488. doi: 10.21037/qims-21-1048.
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A meta-analysis of case studies and clinical characteristics of hypertrophic olivary degeneration secondary to brainstem infarction.
一项关于脑梗死继发橄榄体脑桥小脑萎缩的病例研究和临床特征的荟萃分析。
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Hypertrophic Olivary Degeneration and Palatal or Oculopalatal Tremor.肥厚性橄榄体变性与腭部或动眼腭部震颤
Front Neurol. 2017 Jun 29;8:302. doi: 10.3389/fneur.2017.00302. eCollection 2017.
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Hypertrophic olivary degeneration following surgical resection or gamma knife radiosurgery of brainstem cavernous malformations: an 11-case series and a review of literature.脑干部位海绵状血管畸形手术后或伽玛刀放射手术后出现肥大性橄榄核变性：11 例病例系列及文献复习。
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Oculopalatal tremor and severe late-onset cerebellar ataxia.眼球腭肌震颤与严重迟发性小脑共济失调。
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[Hypertrophic olivary degeneration. MR imaging findings and temporal evolution].[肥大性橄榄体变性。磁共振成像表现及时间演变]
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