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在基于社区的肺癌 CT 筛查计划中,加入非增强腹部 CT 扫描筛查肾癌和其他腹部病变的可接受性:一项定性研究。

Acceptability of adding a non-contrast abdominal CT scan to screen for kidney cancer and other abdominal pathology within a community-based CT screening programme for lung cancer: A qualitative study.

机构信息

Department of Public Health and Primary Care, University of Cambridge, Cambridge, United Kingdom.

Department of Oncology, University of Cambridge, Cambridge, United Kingdom.

出版信息

PLoS One. 2024 Jul 1;19(7):e0300313. doi: 10.1371/journal.pone.0300313. eCollection 2024.

Abstract

OBJECTIVES

The Yorkshire Kidney Screening Trial (YKST) is a feasibility study of adding non-contrast abdominal CT scanning to screen for kidney cancer and other abdominal malignancies to community-based CT screening for lung cancer within the Yorkshire Lung Screening Trial (YLST). This study explored the acceptability of the combined screening approach to participants and healthcare professionals (HCPs) involved in the trial.

METHODS

We conducted semi-structured interviews with eight HCPs and 25 participants returning for the second round of scanning within YLST, 20 who had taken up the offer of the additional abdominal CT scan and five who had declined. Transcripts were analysed using thematic analysis, guided by the Theoretical Framework of Acceptability.

RESULTS

Overall, combining the offer of a non-contrast abdominal CT scan alongside the low-dose thoracic CT was considered acceptable to participants, including those who had declined the abdominal scan. The offer of the additional scan made sense and fitted well within the process, and participants could see benefits in terms of efficiency, cost and convenience both for themselves as individuals and also more widely for the NHS. Almost all participants made an instant decision at the point of initial invitation based more on trust and emotions than the information provided. Despite this, there was a clear desire for more time to decide whether to accept the scan or not. HCPs also raised concerns about the burden on the study team and wider healthcare system arising from additional workload both within the screening process and downstream following findings on the abdominal CT scan.

CONCLUSIONS

Adding a non-contrast abdominal CT scan to community-based CT screening for lung cancer is acceptable to both participants and healthcare professionals. Giving potential participants prior notice and having clear pathways for downstream management of findings will be important if it is to be offered more widely.

摘要

目的

约克郡肾脏筛查试验(YKST)是一项可行性研究,旨在将非增强型腹部 CT 扫描添加到基于社区的肺癌 CT 筛查中,以筛查肺癌,该研究是在约克郡肺癌筛查试验(YLST)中进行的。本研究探讨了这种联合筛查方法对参与试验的参与者和医疗保健专业人员(HCP)的可接受性。

方法

我们对 8 名 HCP 和 25 名在 YLST 中进行第二轮扫描的参与者进行了半结构化访谈,其中 20 名参与者接受了额外的腹部 CT 扫描,5 名参与者拒绝了。根据可接受性的理论框架,使用主题分析方法对转录本进行分析。

结果

总体而言,参与者,包括那些拒绝腹部扫描的参与者,认为同时提供非增强型腹部 CT 扫描和低剂量胸部 CT 扫描是可以接受的。提供额外的扫描是有意义的,并且非常适合该过程,参与者可以看到在效率、成本和便利性方面的好处,无论是对个人还是对国民保健制度(NHS)而言。几乎所有参与者在最初邀请时都根据信任和情绪做出了即时决定,而不是基于提供的信息。尽管如此,他们还是非常希望有更多的时间来决定是否接受扫描。HCP 还对由于筛查过程中以及腹部 CT 扫描结果下游的额外工作量给研究团队和更广泛的医疗保健系统带来的负担表示担忧。

结论

将非增强型腹部 CT 扫描添加到社区为基础的肺癌 CT 筛查中,参与者和医疗保健专业人员均表示接受。如果要更广泛地提供这种方法,让潜在的参与者提前通知,并为发现结果提供明确的下游管理途径将非常重要。

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