Nazarea A D, Bloch D P, Semrau A C
Proc Natl Acad Sci U S A. 1985 Aug;82(16):5337-41. doi: 10.1073/pnas.82.16.5337.
Second-order spectral analysis is used to detect rigorously and to characterize the principal periodicities in the positions of conserved sequences common to tRNAs and rRNAs. It is shown that the shared periodicity having the largest spectral amplitude is 9, followed by 8 and 10, thus forming a closed triad of significant multiplets centered at 9 bases. This conclusion is proposed to reflect a closed triadic set of fundamental tandem repeat lengths in a class of ancestral macromolecules possessing a restricted sequence symmetry. The terms "remanent" and "archeomodular" are used to describe a relic modular format, traces of which are shown here to persist despite the changes that have occurred in the primary structures of ribonucleic acids during the course of their evolution.
二阶谱分析用于严格检测和表征tRNA和rRNA共有的保守序列位置中的主要周期性。结果表明,具有最大谱振幅的共享周期性为9,其次是8和10,从而形成了以9个碱基为中心的显著多重峰的封闭三元组。该结论被认为反映了一类具有受限序列对称性的祖先大分子中基本串联重复长度的封闭三元组集合。术语“残留”和“原模块”用于描述一种残留的模块形式,尽管核糖核酸在其进化过程中一级结构发生了变化,但此处显示其痕迹仍然存在。