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转运RNA-核糖体RNA序列同源性:共同进化起源的证据?

tRNA-rRNA sequence homologies: evidence for a common evolutionary origin?

作者信息

Bloch D P, McArthur B, Widdowson R, Spector D, Guimaraes R C, Smith J

出版信息

J Mol Evol. 1983;19(6):420-8. doi: 10.1007/BF02102317.

Abstract

Many tRNAs of E. coli and yeast contain stretches whose base sequences are similar to those found in their respective rRNAs. The matches are too frequent and extensive to be attributed to coincidence. They are distributed without discernible pattern along and among the RNAs and between the two species. They occur in loops as well as in stems, among both conserved and non-conserved regions. Their distributions suggest that they reflect common ancestral origins rather than common functions, and that they represent true homologies.

摘要

大肠杆菌和酵母的许多转运RNA(tRNA)含有一些片段,其碱基序列与各自核糖体RNA(rRNA)中的碱基序列相似。这些匹配过于频繁和广泛,不可能是巧合。它们沿着RNA以及在RNA之间、两个物种之间无明显规律地分布。它们出现在环和茎中,存在于保守区域和非保守区域。它们的分布表明,它们反映的是共同的祖先起源而非共同的功能,并且代表真正的同源性。

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