3D打印的通风管及其对生物模型的影响。
3D printed ventilation tubes and their effect on biological models.
作者信息
Govea-Camacho Luis Humberto, Castillo-López Irma Yolanda, Carbajal-Castillo Sergio Alejandro, Gonzalez-Ojeda Alejandro, Cervantes-Guevara Gabino, Cervantes-Pérez Enrique, Ramírez-Ochoa Sol, Vázquez-Sánchez Sergio Jiram, Delgado-Hernández Gonzalo, Tavares-Ortega Jaime Alberto, González-Muñoz Samantha Emily, Fuentes-Orozco Clotilde
机构信息
Departamento de Fisiología, Centro Universitario de Ciencias de la Salud, Universidad de Guadalajara, Guadalajara, Jalisco, Mexico.
Departamento de Otorrinolaringología y Cirugía de Cabeza y Cuello, Hospital de Especialidades, Centro Médico Nacional de Occidente, Guadalajara, México.
出版信息
3D Print Med. 2024 Jul 2;10(1):22. doi: 10.1186/s41205-024-00225-y.
BACKGROUND
Acute otitis media (AOM) causes inflammation and hearing loss. Ventilation tubes are key in treatment. 3D printing improves prostheses in otorhinolaryngology, offering precision and greater adaptability.
MATERIALS AND METHODS
An experimental study was conducted with Wistar rats from July to December 2020. 3D tympanostomy tube models were designed, with technical specifications and tests performed on inexpensive 3D printers. The tympanostomy tube was inserted endoscopically.
RESULTS
Procedures were performed on five rats with implants in both ears. Pre-intervention pathologies, such as atical retraction and glue ear, were found. The PLA-printed tympanostomy tube showed improvement after adjustments. Histopathological results revealed significant middle and inner ear damage.
CONCLUSION
In our study, the design and 3D printing of implants fulfilled the desired functions when modified, with a height of 5 mm. Complications included PLA degradation and ear damage. There were no adverse events during observation, highlighting the need for further research on 3D-printed implants.
背景
急性中耳炎（AOM）会引发炎症和听力损失。通气管是治疗的关键。3D打印改善了耳鼻喉科的假体，提供了精确性和更强的适应性。
材料与方法
于2020年7月至12月对Wistar大鼠进行了一项实验研究。设计了3D鼓膜造孔通气管模型，并在廉价的3D打印机上进行了技术规格和测试。通过内镜插入鼓膜造孔通气管。
结果
对5只双耳植入的大鼠进行了手术。发现了干预前的病变，如鼓室回缩和胶耳。经调整后，聚乳酸（PLA）打印的鼓膜造孔通气管显示出改善。组织病理学结果显示中耳和内耳有明显损伤。
结论
在我们的研究中，植入物的设计和3D打印在修改后实现了预期功能，高度为5毫米。并发症包括PLA降解和耳部损伤。观察期间未出现不良事件，这突出表明需要对3D打印植入物进行进一步研究。
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