Department of Geriatrics, University of Connecticut, 263 Farmington Avenue, Farmington, CT 06030, USA.
Clin Geriatr Med. 2024 Aug;40(3):375-384. doi: 10.1016/j.cger.2023.12.011. Epub 2024 Jan 18.
Wound healing is a highly complex natural process, and its failure results in chronic wounds. The causes of delayed wound healing include patient-related and local wound factors. The main local impediments to delayed healing are the presence of nonviable tissue, excessive inflammation, infection, and moisture imbalance. For wounds that can be healed with adequate blood supply, a stepwise approach to identify and treat these barriers is termed wound bed preparation. Currently, a combination of patient-related and local factors, including wound debridement, specialty dressings, and advanced technologies, is available and successfully used to facilitate the healing process.
伤口愈合是一个高度复杂的自然过程，其失败会导致慢性伤口。导致伤口愈合延迟的原因包括患者相关因素和局部伤口因素。导致愈合延迟的主要局部障碍是存在无活力的组织、过度炎症、感染和水分失衡。对于可以通过充足的血液供应愈合的伤口，可以采用逐步的方法来识别和治疗这些障碍，这被称为创面床准备。目前，有一系列的方法可供选择，包括伤口清创、特殊敷料和先进技术，这些方法被成功地用于促进愈合过程。
