Schultz Gregory S, Barillo David J, Mozingo David W, Chin Gloria A
Department Obstetrics and Gynecology, University of Florida, gainesville, FL 32610-0294, USA.
Int Wound J. 2004 Apr;1(1):19-32. doi: 10.1111/j.1742-481x.2004.00008.x.
Management of chronic wounds has progressed from merely assessing the status of a wound to understanding the underlying molecular and cellular abnormalities that prevent the wound from healing. The concept of wound bed preparation has simultaneously evolved to provide a systematic approach to removing these barriers to natural healing and enhancing the effects of advanced therapies. This brief review of wound bed preparation traces the development of these concepts and explains how to apply systematic wound management using the TIME acronym - tissue (non viable or deficient), infection/inflammation, moisture (imbalance) and edge (non advancing or undermined).
慢性伤口的管理已从仅仅评估伤口状况发展到了解阻碍伤口愈合的潜在分子和细胞异常。伤口床准备的概念也同时得到了发展，以提供一种系统的方法来消除这些自然愈合的障碍，并增强先进治疗方法的效果。这篇关于伤口床准备的简要综述追溯了这些概念的发展，并解释了如何使用TIME首字母缩写词（组织[无活力或不足]、感染/炎症、湿度[失衡]和边缘[无进展或侵蚀]）来应用系统的伤口管理。
