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用于溃疡性乳腺癌的除臭垫:安全性与有效性

Deodorant pad for ulcerated breast cancer: safety and efficacy.

作者信息

Ishiba Toshiyuki, Ishida Hirohiko, Inoue Michiaki, Tazoe Yuki, Sakai Mami, Fujita Yuki, Kida Hiroko, Kosaka Taijiro, Ishihara Sakiko, Nara Miyako, Adachi Mio, Saita Chiaki, Goto Risa, Iwamoto Naoko, Nakatsugawa Noriko, Toi Masakazu, Aruga Tomoyuki

机构信息

Breast Center, Tokyo Metropolitan Cancer and Infectious Diseases Center Komagome Hospital, Bunkyo-ku, Japan

Deparment of Breast Surgery, Tokyo Medical and Dental University, Tokyo, Japan.

出版信息

BMJ Support Palliat Care. 2024 Jul 2;14(e2). doi: 10.1136/spcare-2024-005024.

Abstract

OBJECTIVES

APOLLO study, 'efficacy and safety of the deodorAnt Pad against Odour and uLceration for LOcally advanced breast cancer', aimed to assess the safety and efficacy of wearing a deodorant pad in patients with locally advanced breast cancer (LABC) with an ulceration.

METHODS

Komagome Pads were previously developed by Juntendo University and Kao Corporation. In test A, a conventional pad consisting of gauze, a commercially available diaper, pad, etc and the Komagome Pad were compared over 3 days to assess their efficacy and possible improvements for short-term use. In test B, the Komagome Pad was used continuously for 1 month to evaluate its safety during long-term use.

RESULTS

This study included 14 patients in test A and nine in test B. In odour evaluation using sensory testing in test A, nine patients reported more significant efficacy in odour suppression with the Komagome Pad. The odour intensity of the Komagome Pad was lower on the gas chromatography-mass spectrometry. The group with a high level of exudation reported significantly higher satisfaction with the Komagome Pad. In test B, no adverse events were observed.

CONCLUSIONS

A new deodorant pad for LABC demonstrated high safety and deodorant efficacy.

摘要

目的

APOLLO研究,即“除臭垫对局部晚期乳腺癌异味和溃疡的疗效及安全性”,旨在评估在患有溃疡的局部晚期乳腺癌(LABC)患者中使用除臭垫的安全性和疗效。

方法

小菅垫先前由顺天堂大学和花王公司研发。在试验A中,将由纱布、市售尿布、垫子等组成的传统垫子与小菅垫在3天内进行比较,以评估其疗效以及短期使用时可能的改进。在试验B中,连续使用小菅垫1个月,以评估其长期使用期间的安全性。

结果

本研究试验A纳入14例患者,试验B纳入9例患者。在试验A中使用感官测试进行气味评估时,9例患者报告小菅垫在抑制气味方面疗效更显著。在气相色谱 - 质谱分析中,小菅垫的气味强度较低。渗出水平高的组对小菅垫的满意度显著更高。在试验B中,未观察到不良事件。

结论

一种用于局部晚期乳腺癌的新型除臭垫显示出高安全性和除臭效果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fa1c/11671911/1d1536e56ecc/spcare-14-e2-g001.jpg

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