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[肾包膜下测定法,一种新型抗肿瘤药物敏感性试验]

[Subrenal capsule assay, a new sensitivity test for antitumor agents].

作者信息

Sakai Y

出版信息

Gan To Kagaku Ryoho. 1985 Aug;12(8):1535-51.

PMID:3896153
Abstract

The subrenal capsule assay (SRCA) has been developed by Bogden. This simple method using fresh human tumor has much more approximation with clinical procedure than other sensitivity tests. Even from our as yet limited small experiences, its high evaluability and high specificity are promising. Problems inherent to the actual assay and its limitations were reviewed and discussed, including our trial with bone marrow puncture specimens of leukemia, our evaluation criteria and assay-clinical correlations. This method will be widely utilized in several fields of cancer treatment in the near future.

摘要

肾包膜下测定法(SRCA)由博登开发。这种使用新鲜人类肿瘤的简单方法与临床程序的近似度比其他敏感性测试高得多。即使从我们目前有限的小样本经验来看,其高可评估性和高特异性也很有前景。我们回顾并讨论了实际测定法固有的问题及其局限性,包括我们对白血病骨髓穿刺标本的试验、我们的评估标准以及测定法与临床的相关性。这种方法在不久的将来将在癌症治疗的多个领域得到广泛应用。

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