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老年人居住的养老院中的药物治疗方案:一项描述药物数量、方案复杂性、高风险处方和潜在药物不足的重复横断面研究。

Medicines Regimens Charted for Older People Living in Residential Aged Care: A Repeated Cross-Sectional Study Describing the Number of Medicines, Regimen Complexity, High-Risk Prescribing, and Potential Underprescribing.

机构信息

School of Allied Health, The University of Western Australia, Perth, Western Australia, Australia.

Ryman Healthcare, Christchurch, Canterbury, New Zealand.

出版信息

J Am Med Dir Assoc. 2024 Jun;25(6):104944. doi: 10.1016/j.jamda.2024.01.013. Epub 2024 Feb 28.

DOI:10.1016/j.jamda.2024.01.013
PMID:38428832
Abstract

OBJECTIVE

We aimed to explore medicines regimens charted for older people living in residential aged care facilities (RACFs).

DESIGN

Repeated cross-sectional study using routinely collected data sampled in a cross-sectional manner at 11 time points (day of admission, then at 1, 3, 7, 14, and 30 days, and 3, 6, 12, 18, and 24 months post admission).

SETTING AND PARTICIPANTS

The cohort is set in 34 RACFs managed by a single Australasian provider. People aged ≥65 years admitted to permanent care between January 1, 2017, and October 1, 2021, with medicines charted on the date of admission.

METHODS

Medicines charted were evaluated for potentially suboptimal prescribing including number of medicines, high-risk prescribing (eg, potentially inappropriate medicines, anticholinergic burden), and potential underprescribing.

RESULTS

The 3802 residents in the final cohort had a mean age of 84.9 ± 7.2 years at admission. At least 1 example of suboptimal prescribing was identified in 3479 (92%) residents at admission increasing to 1410 (97%) at 24 months. The number of medicines charted for each resident increased over time from 6.0 ± 3.8 regular and 2.8 ± 2.7 as required medicines at admission to 8.9 ± 4.1 regular and 8.1 ± 3.7 as required medicines at 24 months. Anticholinergic drug burden increased from 1.6 ± 2.4 at admission to 3.0 ± 2.8 at 24 months. Half the residents (2173; 57%) used at least 1 potentially inappropriate medicine at admission, which rose to nearly three-quarters (1060; 73%) at 24 months admission.

CONCLUSION AND IMPLICATIONS

The total number of medicines charted for older adults living in RACFs increases with length of stay, with charted as required medicines nearly tripling. Effective interventions to optimize medicines use in this vulnerable population are required.

摘要

目的

本研究旨在探讨居住在养老院的老年人的用药方案。

设计

本研究为重复的横截面研究,使用在 11 个时间点(入院当天,然后在入院后 1、3、7、14 和 30 天,以及 3、6、12、18 和 24 个月)以横截面方式采集的常规收集数据。

地点和参与者

该队列位于一家澳大拉西亚供应商管理的 34 家养老院中。2017 年 1 月 1 日至 2021 年 10 月 1 日期间,年龄≥65 岁并在入院当天记录用药情况的患者被纳入研究。

方法

评估入院时记录的药物治疗方案是否存在潜在的不适当处方,包括用药数量、高风险处方(如潜在不适当药物、抗胆碱能药物负担)和潜在的药物剂量不足。

结果

最终队列中的 3802 名居民入院时的平均年龄为 84.9 ± 7.2 岁。在入院时,3479 名(92%)居民至少存在 1 种不适当处方,而在 24 个月时,这一比例增加到 1410 名(97%)。每位居民记录的药物数量随着时间的推移而增加,从入院时的 6.0 ± 3.8 种常规药物和 2.8 ± 2.7 种按需药物增加到 24 个月时的 8.9 ± 4.1 种常规药物和 8.1 ± 3.7 种按需药物。抗胆碱能药物负担从入院时的 1.6 ± 2.4 增加到 24 个月时的 3.0 ± 2.8。入院时,一半的居民(2173 名;57%)至少使用了 1 种潜在不适当的药物,而在 24 个月时,这一比例上升至近四分之三(1060 名;73%)。

结论和意义

居住在养老院的老年人记录的药物总数随着住院时间的延长而增加,记录的按需药物几乎增加了两倍。需要有效的干预措施来优化这一脆弱人群的药物使用。

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