布隆迪卡门格教学医院血库献血者的输血传播感染。
Transfusion transmitted infections among blood donors of Kamenge Teaching Hospital blood bank in Burundi.
机构信息
Department of Dermatology and Venereology, Faculty of Medicine, Kamenge Teaching Hospital of University of Burundi, P. Box 1020, Bujumbura, Burundi.
Department of Dermatology, Cosmetology and Venereology, Shenzhen Hospital of Southern Medical University, Shenzhen, Guangdong, China.
出版信息
Afr Health Sci. 2024 Mar;24(1):94-103. doi: 10.4314/ahs.v24i1.12.
BACKGROUND
The current risk of contracting a transfusion transmitted infections (TTIs) is unknown in Burundi.
OBJECTIVES
The aim of this study was to assess sociodemographic profiles of blood bank donors at Kamenge Teaching Hospital, the prevalence and associated risk factors of HIV, syphilis, HBV and HCV from 2015 to 2020.
METHODS
We conducted a cross-sectional study including all blood donors of Kamenge Teaching Hospital blood bank. During this study, 1370 blood samples were screened for HIV, Syphilis, HBV and HCV. We calculated prevalence of TTIs and performed logistic regression to know associated risk factors.
RESULTS
Blood donors were males at 77% and 23% females. They were mostly students (54.2%). On screening, 83 blood samples (6.06%) were seropositive for at least one TTI. The overall prevalence rate of HIV, Syphilis, HBV and HCV among blood donors was 1.3%, 0.2% ,1.6%, 2.9% respectively. There was difference in distribution of the four TTIs among blood donors which is statistically significant (x=33.997, ϱ-value<0.001). Private donors were associated with a high risk of syphilis and being a first-time donor was associated with a high HBV risk factor.
CONCLUSION
The prevalence of TTIs found still to be high; mandatory and continuous screening is necessary.
背景
目前尚不清楚布隆迪的输血传播感染（TTI）的风险。
目的
本研究旨在评估卡门格教学医院献血者的社会人口统计学特征，以及 2015 年至 2020 年期间 HIV、梅毒、HBV 和 HCV 的流行情况及其相关危险因素。
方法
我们进行了一项横断面研究，包括卡门格教学医院血库的所有献血者。在此期间，对 1370 份血样进行了 HIV、梅毒、HBV 和 HCV 的筛查。我们计算了 TTI 的流行率，并进行了逻辑回归以了解相关的危险因素。
结果
献血者中男性占 77%，女性占 23%。他们大多是学生（54.2%）。在筛查中，83 份血液样本（6.06%）至少对一种 TTI 呈血清阳性。献血者中 HIV、梅毒、HBV 和 HCV 的总流行率分别为 1.3%、0.2%、1.6%和 2.9%。四种 TTI 在献血者中的分布存在差异，且具有统计学意义（x=33.997，p 值<0.001）。私人献血者与梅毒高风险相关，初次献血者与 HBV 高风险因素相关。
结论
发现 TTI 的流行率仍然很高；需要进行强制性和持续的筛查。
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