Habibu Ismail, Abubakar Bashir Mohammed, Moi Ibrahim Musa, Abdulrazaq Rabiu
Department of Biological Sciences, Bauchi State University Gadau, PMB 065, Bauchi, Nigeria.
Department of Microbiology, Bauchi State University Gadau, PMB 065, Bauchi, Nigeria.
BMC Infect Dis. 2025 Apr 30;25(1):638. doi: 10.1186/s12879-025-11024-z.
Transfusion-transmitted infections (TTIs), such as HIV, HBV, HCV, and Syphilis, present considerable difficulties in maintaining blood quality despite the critical role of blood transfusion in emergency medical care. This study aims to ascertain the prevalence of these infections and the factors that increase their risk among those who donate blood.
A cross-sectional study was conducted at the Federal Medical Center in Azare, involving 400 blood donors. Serological tests were conducted for HBV, HCV, HIV, and syphilis, and sociodemographic data was collected through a structured questionnaire. The univariate and multivariate logistic regression tests were employed to detect associated risk factors, with a significance level set at P < 0.05.
Of the total blood donors, 17.00% (68/400) tested positive for at least one TTIs. The presence of HIV, HBV, HCV, and syphilis was identified in 2.8% (11/400), 8.3% (33/400), 1.8% (7/400), and 4.3% (17/400) of the donors, respectively. Multivariate analysis, after adjustments with various variables, indicates only commercial blood donors [Adjusted Odds Ratio (AOR) (95% CI): 14.63 (1.76-121.27)] and multiple sexual partners [AOR (95% CI): 5.40 (1.28-22.70)] were associated with HIV, while blood transfusion and piercing or tattoo were associated with HBV. Multiple sexual partners and a history of STDs were associated with syphilis infection.
TTIs such as HIV, HBV, HCV, and syphilis were detected among the blood donors, with HBV being the most common. The findings highlight a gender disparity in blood donation, with voluntary donors comprising the majority; nevertheless, commercial donors had the highest prevalence of TTIs. Enhanced donor screening and public awareness are crucial for blood safety.
Not applicable.
尽管输血在紧急医疗救治中发挥着关键作用，但输血传播感染（TTIs），如艾滋病毒、乙肝病毒、丙肝病毒和梅毒，给维持血液质量带来了相当大的困难。本研究旨在确定这些感染的流行情况以及在献血者中增加其风险的因素。
在阿扎雷的联邦医疗中心进行了一项横断面研究，涉及400名献血者。对乙肝病毒、丙肝病毒、艾滋病毒和梅毒进行了血清学检测，并通过结构化问卷收集了社会人口学数据。采用单因素和多因素逻辑回归检验来检测相关风险因素，显著性水平设定为P<0.05。
在所有献血者中，17.00%（68/400）至少一种TTIs检测呈阳性。分别在2.8%（11/400）、8.3%（33/400）、1.8%（7/400）和4.3%（17/400）的献血者中检测到艾滋病毒、乙肝病毒、丙肝病毒和梅毒。在对各种变量进行调整后的多因素分析表明，只有商业献血者[调整后的优势比（AOR）（95%置信区间）：14.63（1.76 - 121.27）]和多个性伴侣[AOR（95%置信区间）：5.40（1.28 - 22.70）]与艾滋病毒有关，而输血和穿孔或纹身与乙肝病毒有关。多个性伴侣和性传播疾病史与梅毒感染有关。
在献血者中检测到艾滋病毒、乙肝病毒、丙肝病毒和梅毒等TTIs，其中乙肝病毒最为常见。研究结果凸显了献血中的性别差异，自愿献血者占大多数；然而，商业献血者中TTIs的患病率最高。加强献血者筛查和公众意识对血液安全至关重要。
不适用。
