加纳一家地区医院献血者的输血传播感染：6 年趋势分析（2017-2022）。
Transfusion-Transmissible Infections Among Blood Donors in a Regional Hospital in Ghana: A 6-Year Trend Analysis (2017-2022).
机构信息
Department of Population and Behavioural Sciences, School of Public Health, University of Health and Allied Sciences, Ho, Ghana.
School of Public Health, University of Health and Allied Sciences, Hohoe, Ghana.
出版信息
J Int Assoc Provid AIDS Care. 2024 Jan-Dec;23:23259582241274305. doi: 10.1177/23259582241274305.
BACKGROUND
This study determined the trends of transfusion-transmissible infections (TTIs) among blood donors in a regional hospital in Ghana from 2017 to 2022.
METHODS
A retrospective analysis was conducted on 6339 blood donor records. Data were analyzed using STATA version 17.0 at the 0.05 significance level.
RESULTS
The prevalence of TTIs was 31.4% in 2017, 13.8% in 2018, 20.4% in 2019, 9.5% in 2020, 9.6% in 2021, and 11.7% in 2022. There were significant associations between hepatitis C virus (HCV), Syphilis, and sex (OR = 2.06; 95% CI [1.29-3.30]; = .003) and (OR = 2.28; 95% CI [1.48-3.54]; < .001), respectively. Blood donors aged 20-29 were more likely to be infected with hepatitis B virus (OR = 1.96; 95% CI [1.28-2.99]; = .002). Blood donors aged 40-49 had higher odds of infection with HCV (OR = 3.36; 95% CI [2.02-5.57]; < .001) and Syphilis (OR = 3.79; 95% CI [2.45-5.87]; < .001).
CONCLUSION
The study highlights the need to implement targeted prevention strategies for donors with a higher TTI prevalence.
背景
本研究旨在确定 2017 年至 2022 年加纳一家地区医院献血者中输血传播感染（TTI）的趋势。
方法
对 6339 份献血者记录进行回顾性分析。数据使用 STATA 版本 17.0 进行分析，显著性水平为 0.05。
结果
2017 年、2018 年、2019 年、2020 年、2021 年和 2022 年 TTI 的患病率分别为 31.4%、13.8%、20.4%、9.5%、9.6%和 11.7%。丙型肝炎病毒（HCV）、梅毒和性别之间存在显著关联（OR=2.06；95%CI[1.29-3.30]；=0.003）和（OR=2.28；95%CI[1.48-3.54]；<0.001）。20-29 岁的献血者更有可能感染乙型肝炎病毒（OR=1.96；95%CI[1.28-2.99]；=0.002）。40-49 岁的献血者感染 HCV（OR=3.36；95%CI[2.02-5.57]；<0.001）和梅毒（OR=3.79；95%CI[2.45-5.87]；<0.001）的几率更高。
结论
该研究强调需要针对 TTI 患病率较高的献血者实施有针对性的预防策略。
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