Nikolaevskaia V R, Chernikov M P
Biull Eksp Biol Med. 1985 Aug;100(8):139-42.
It has been shown that in postnatal animals, the activity of lysosomal proteinases in the distal part of the small intestine was considerably higher than in the proximal one. With transition from milk to definitive nutrition, the activity of lysosomal proteinases gets equalized in the proximal and distal parts of the small intestine. The data concerning the proximo-distal gradient of distribution of the activity of lysosomal proteinases have been supported. Transition from milk to definitive nutrition has given rise to ultrastructural alterations in the lysosomal apparatus.
研究表明，在出生后的动物中，小肠远端溶酶体蛋白酶的活性明显高于近端。随着从母乳到常规营养的转变，小肠近端和远端溶酶体蛋白酶的活性趋于平衡。有关溶酶体蛋白酶活性分布的近端 - 远端梯度的数据得到了证实。从母乳到常规营养的转变导致了溶酶体细胞器的超微结构改变。
