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[出生后个体发育中小肠溶酶体蛋白酶活性]

[Lysosomal proteinase activity in the small intestine in postnatal ontogeny].

作者信息

Nikolaevskaia V R

出版信息

Vopr Med Khim. 1982 Jul-Aug;28(4):75-7.

PMID:7051549
Abstract

A lysosomal fraction was isolated from various parts of small intestinal mucose of rats at postnatal periods of growth as well as from adult animals. Activity of marked lysosomal enzymes (acid phosphatase and cathepsins) was 3-fold higher in ileum than the jejunum of young rats at the lactation periods of growth. In adult animals the enzymatic activity was similar both in proximal and distal parts of small intestines. At the postnatal period of growth the lysosomal enzymes appear to carry out a compensatory function, participating in final steps of milk protein digestion.

摘要

从出生后不同生长阶段的大鼠小肠黏膜各部位以及成年动物中分离出溶酶体组分。在生长哺乳期,幼鼠回肠中显著的溶酶体酶(酸性磷酸酶和组织蛋白酶)活性比空肠高3倍。在成年动物中,小肠近端和远端的酶活性相似。在出生后的生长阶段,溶酶体酶似乎发挥着补偿功能,参与乳蛋白消化的最后步骤。

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