New York State Department of Health, Wadsworth Center, Empire State Plaza, Albany, New York 12237, United States.
Department of Environmental Health Sciences, School of Public Health, State University of New York at Albany, Albany, New York 12237, United States.
Environ Sci Technol. 2024 Jul 16;58(28):12400-12408. doi: 10.1021/acs.est.4c03131. Epub 2024 Jul 5.
Liquid crystal monomers (LCMs) are biphenyl- or cyclohexane-based organic chemicals used in electronic digital displays, and several of them possess bioaccumulative and toxic properties. Little is known about their occurrence in indoor dust from the United States. We analyzed 60 LCMs in 104 residential indoor dust samples collected from 16 states across the United States. Forty-seven of 60 LCMs were detected in dust samples at a median ∑LCM concentration of 402 ng/g (range: not detected to 4300 ng/g). Trans-4-propylcyclohexyl trans,trans-4'-propylbicyclohexyl-4-carboxylate (MPVBC) and (trans,trans)-4-fluorophenyl 4'-pentyl-[1,1'-bi(cyclohexane)]-4-carboxylate (FPeBC) were frequently detected in dust samples. We investigated potential sources of LCMs in dust by determining concentrations and profiles of these chemicals in smartphone screens, desktop and laptop computer monitors, and displays of other electronic devices and found that profiles in smartphones matched closely with those found in dust. The calculated median daily intake of ∑LCM through dust ingestion was 1.19 ng/kg bw/d for children, whereas that through dermal absorption was 0.18 ng/kg bw/d for adults in the United States.
液晶单体 (LCMs) 是一种基于联苯或环己烷的有机化学品，用于电子数字显示器，其中几种具有生物蓄积性和毒性。关于它们在美国室内灰尘中的存在情况知之甚少。我们分析了从美国 16 个州采集的 104 个住宅室内灰尘样本中的 60 种 LCM。在灰尘样本中检测到 47 种 LCM，∑LCM 浓度中位数为 402ng/g（范围：未检出至 4300ng/g）。反式-4-丙基环己基反式，反式-4'-丙基双环己基-4-羧酸酯（MPVBC）和（反式，反式）-4-氟苯基 4'-戊基-[1,1'-双（环己烷）]-4-羧酸酯（FPeBC）在灰尘样本中经常被检测到。我们通过确定智能手机屏幕、台式和笔记本电脑显示器以及其他电子设备的这些化学物质的浓度和分布来研究灰尘中 LCM 的潜在来源，并发现智能手机中的分布与灰尘中的分布非常吻合。通过灰尘摄入计算的∑LCM 的儿童每日摄入量中位数为 1.19ng/kg bw/d，而通过皮肤吸收的成年人每日摄入量中位数为 0.18ng/kg bw/d。
