Morley C G, Bezkorovainy A
Int J Biochem. 1985;17(5):553-64. doi: 10.1016/0020-711x(85)90286-1.
Receptor mediated endocytosis has been proposed as the method of cellular iron uptake from transferrin (TF). However, the experimental evidence for endocytosis in every situation is found wanting. This is particularly true for the hepatocyte where an alternative mechanism of iron release at the cell surface can account for all iron uptake. It may be, that under appropriate physiological conditions (e.g. degree of iron saturation of TF) cells may take up iron by either an endocytotic or nonendocytotic mechanism.
受体介导的内吞作用被认为是细胞从转铁蛋白（TF）摄取铁的方式。然而，在每种情况下内吞作用的实验证据都不足。对于肝细胞来说尤其如此，在肝细胞表面存在一种铁释放的替代机制，可以解释所有的铁摄取。在适当的生理条件下（如TF的铁饱和度），细胞可能通过内吞或非内吞机制摄取铁。
