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手术治疗腹茧症并发肠坏死及术后抑郁意外缓解 1 例报告。

Managing abdominal cocoon syndrome complicated by intestinal necrosis and unexpected amelioration of depression after surgery: a case report.

机构信息

Department of General Surgery, Tianjin Union Medical Center, The Affiliated Hospital of Nankai University, Tianjin, 300121, China.

Tianjin Key Laboratory of General Surgery in Construction, Tianjin Union Medical Center, Tianjin, 300121, China.

出版信息

J Med Case Rep. 2024 Jul 6;18(1):322. doi: 10.1186/s13256-024-04650-9.

Abstract

BACKGROUND

Abdominal cocoon is a very uncommon yet dangerous cause of intestinal obstruction.

CASE PRESENTATION

We present a case of a 62-year-old Asian male patient with a history of depression who exhibited an idiopathic abdominal cocoon complicated by necrosis. Upon laparotomy investigation, nearly the entire small intestine was enveloped in a thick membrane resembling a cocoon, and it was discovered that he lacked a greater omentum. The patient recovered well and was discharged on an oral diet on the 20th day following surgery. During the 3-month follow-up, the patient was asymptomatic, even gaining 10 kg in weight, and noted that his depression had improved.

CONCLUSIONS

Small bowel obstruction presents with nonspecific symptoms, posing challenges in differential diagnosis. Contrast-enhanced computed tomography is recommended since it facilitates precise preoperative assessment, optimizing surgical planning and reducing postoperative complications. Remarkably, cessation of antidepressant medication post-surgery hints at a potential correlation between omental deficit, gut microbiota alterations, and depressive symptoms.

摘要

背景

腹腔茧是一种非常罕见但危险的肠梗阻病因。

病例介绍

我们报告了一例 62 岁亚裔男性抑郁症患者,他患有特发性腹腔茧并伴有坏死。剖腹探查发现,几乎整个小肠都被一层厚厚的膜包裹着,类似于茧,并且发现他没有大网膜。患者术后恢复良好,第 20 天开始口服饮食并出院。在 3 个月的随访中,患者无症状,甚至体重增加了 10 公斤,他注意到自己的抑郁症状有所改善。

结论

小肠梗阻的症状不具有特异性,这给鉴别诊断带来了挑战。建议进行增强 CT 检查,因为它有助于术前的精确评估,优化手术计划,并减少术后并发症。值得注意的是,术后停止使用抗抑郁药物提示大网膜缺失、肠道微生物群改变和抑郁症状之间可能存在关联。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/efc1/11227164/5d259b7ffd68/13256_2024_4650_Fig1_HTML.jpg

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