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袖状胃切除术后胃食管反流病的实际发生率——一项前瞻性pH监测研究。

The real occurrence of gastroesophageal reflux disease after sleeve gastrectomy - a prospective pH-monitoring study.

作者信息

Dowgiałło-Gornowicz Natalia, Lech Pawel

机构信息

Department of General, Minimally Invasive, and Elderly Surgery, Collegium Medicum, University of Warmia and Mazury, Olsztyn, Poland.

出版信息

Wideochir Inne Tech Maloinwazyjne. 2024 Jun;19(2):205-210. doi: 10.5114/wiitm.2024.138521. Epub 2024 Apr 3.

DOI:10.5114/wiitm.2024.138521
PMID:38973794
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11223549/
Abstract

INTRODUCTION

Sleeve gastrectomy (SG) is currently the most frequently performed bariatric procedure in the world. However, the occurrence of gastroesophageal reflux disease (GERD) after SG remains controversial and questionable.

AIM

To determine the occurrence of GERD after SG using a pH-monitoring study.

MATERIAL AND METHODS

This is a prospective study involving patients undergoing SG in one surgical centre. Inclusion criteria were eligibility for bariatric surgery, no symptoms of GERD, normal gastroscopy, and pH-monitoring before the surgery. Postoperative examinations were performed 6 months after surgery.

RESULTS

A total of 38 patients were analysed in the study. The mean age was 44.9 years, and the mean preoperative BMI was 42.6 kg/m. Before surgery, all patients had normal pH values. After surgery, mean acid exposure time (AET), number of refluxes, and DeMeester score increased statistically significantly (p < 0.001). 27 (71.1%) patients each had AET > 6%, but only 9 (23.7%) reported GERD symptoms and the need for PPIs. The correlation between AET and %TWL was moderate positive, and the correlation between DeMeester score and %TWL was low positive (p = 0.011, p = 0.014, respectively).

CONCLUSIONS

GERD after SG seems to be a significant problem. More than two-thirds of patients had de novo GERD after SG in pH-monitoring, but only one-quarter of them required PPIs.

摘要

引言

袖状胃切除术(SG)是目前世界上最常施行的减肥手术。然而,SG术后胃食管反流病(GERD)的发生仍存在争议且值得怀疑。

目的

通过pH监测研究确定SG术后GERD的发生率。

材料与方法

这是一项前瞻性研究,涉及在一个手术中心接受SG的患者。纳入标准为符合减肥手术条件、无GERD症状、胃镜检查正常且术前进行pH监测。术后6个月进行检查。

结果

本研究共分析了38例患者。平均年龄为44.9岁,术前平均BMI为42.6kg/m²。术前所有患者的pH值均正常。术后,平均酸暴露时间(AET)、反流次数和DeMeester评分在统计学上显著增加(p<0.001)。27例(71.1%)患者的AET>6%,但只有9例(23.7%)报告有GERD症状且需要使用质子泵抑制剂(PPI)。AET与%TWL之间的相关性为中度正相关,DeMeester评分与%TWL之间的相关性为低度正相关(分别为p = 0.011,p = 0.014)。

结论

SG术后GERD似乎是一个严重问题。超过三分之二的患者在pH监测中术后出现新发GERD,但其中只有四分之一需要使用PPI。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4a0f/11223549/86274becd2d7/WIITM-19-53896-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4a0f/11223549/0de0dbc52778/WIITM-19-53896-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4a0f/11223549/12e588db1c8f/WIITM-19-53896-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4a0f/11223549/86274becd2d7/WIITM-19-53896-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4a0f/11223549/0de0dbc52778/WIITM-19-53896-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4a0f/11223549/12e588db1c8f/WIITM-19-53896-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4a0f/11223549/86274becd2d7/WIITM-19-53896-g003.jpg

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2
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3
Updates to the modern diagnosis of GERD: Lyon consensus 2.0.
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Gut. 2024 Jan 5;73(2):361-371. doi: 10.1136/gutjnl-2023-330616.
4
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