Cassee Flemming R, Bleeker Eric A J, Durand Cyrille, Exner Thomas, Falk Andreas, Friedrichs Steffi, Heunisch Elisabeth, Himly Martin, Hofer Sabine, Hofstätter Norbert, Hristozov Danail, Nymark Penny, Pohl Anna, Soeteman-Hernández Lya G, Suarez-Merino Blanca, Valsami-Jones Eugenia, Groenewold Monique
National Institute of Public Health and the Environment (RIVM), the Netherlands & Institute for Risk Assessment Sciences, Utrecht University, Utrecht, the Netherlands.
National Institute of Public Health and the Environment (RIVM), the Netherlands.
Comput Struct Biotechnol J. 2024 Jun 2;25:105-126. doi: 10.1016/j.csbj.2024.05.018. eCollection 2024 Dec.
The adoption of innovative advanced materials holds vast potential, contingent upon addressing safety and sustainability concerns. The European Commission advocates the integration of Safe and Sustainable by Design (SSbD) principles early in the innovation process to streamline market introduction and mitigate costs. Within this framework, encompassing ecological, social, and economic factors is paramount. The NanoSafety Cluster (NSC) delineates key safety and sustainability areas, pinpointing unresolved issues and research gaps to steer the development of safe(r) materials. Leveraging FAIR data management and integration, alongside the alignment of regulatory aspects, fosters informed decision-making and innovation. Integrating circularity and sustainability mandates clear guidance, ensuring responsible innovation at every stage. Collaboration among stakeholders, anticipation of regulatory demands, and a commitment to sustainability are pivotal for translating SSbD into tangible advancements. Harmonizing standards and test guidelines, along with regulatory preparedness through an exchange platform, is imperative for governance and market readiness. By adhering to these principles, the effective and sustainable deployment of innovative materials can be realized, propelling positive transformation and societal acceptance.
采用创新的先进材料具有巨大潜力，但前提是要解决安全和可持续性问题。欧盟委员会主张在创新过程早期就融入“设计安全与可持续”（SSbD）原则，以简化市场引入并降低成本。在此框架内，涵盖生态、社会和经济因素至关重要。纳米安全集群（NSC）划定了关键的安全和可持续性领域，找出未解决的问题和研究差距，以指导更安全材料的开发。利用公平的数据管理和整合，以及使监管方面保持一致，有助于做出明智的决策和推动创新。整合循环性和可持续性需要明确的指导，确保在每个阶段都进行负责任的创新。利益相关者之间的合作、对监管要求的预期以及对可持续性的承诺，对于将SSbD转化为切实的进步至关重要。协调标准和测试指南，以及通过交流平台做好监管准备，对于治理和市场准备至关重要。通过遵循这些原则，可以实现创新材料的有效和可持续部署，推动积极变革并获得社会认可。
