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睾丸疾病:来自尼日利亚一家三级医疗中心的临床病理报告。

Testicular Disease: A Clinico-Pathological Report from a Nigerian Tertiary Health Center.

作者信息

Emmanuel Innocent, Akpa Philip Ojile, Amaike Chikwendu, Winnie Jummai Sa'a, Otene Benjamin Samuel, Dallang Bamnan Collins, Adedeji Bankole Koffi, William Bapigaan Audu, Abaniwo Samuel, Awesu Sulaimon Adebayo, Longwap Saleh Abdulazis, Nansok Titus Fadok, Nabasu Lemech Ezra, Mandong Barnabas Mafala

机构信息

Department of Pathology, University of Jos, Plateau State.

Department of Anatomic Pathology and Forensic Medicine, Jos University Teaching Hospital, Plateau State.

出版信息

Niger Med J. 2023 Jul 2;64(3):307-313. eCollection 2023 May-Jun.

Abstract

BACKGROUND

The testes are the male reproductive glands and the homolog of the ovary in females performing critical functions. Pathologic conditions could arise from the testes and blunt or completely obliterate these functions leading to clinically overt or covert sequelae. The aim of this research is to study the pattern of histologically diagnosed testicular disease in relation to clinical features at the Jos University Teaching Hospital between January 2012 and December 31st, 2021.

METHODOLOGY

This study is a retrospective analysis of all cases of testicular biopsies. All histologically diagnosed testicular lesions were identified from the departmental records and clinical data obtained further from the patients' folder at the Medical Records Department.

RESULTS

Four hundred and thirty (430) biopsies were seen, of which 304 (70.7%) were orchidectomy specimens. The commonest histological diagnosis was testicular atrophy accounting for 328(76.3%) cases. Testicular torsion is followed by 42(9.8%) cases. Together, inflammatory conditions accounted for 36(8.4%) cases out of which granulomatous inflammation made up 52.3% of cases. There were 16(3.7%) neoplastic conditions all of which were malignant, out of which 6(37.5%) were seminomas. The age range, mean, median and modal age was 1-90 years, 53.4 +21.3years, 60 years and 70 years respectively. Prostatic carcinoma therapy in the form of bilateral orchidectomy was the major indication for surgery.

CONCLUSION

The majority of testicular lesions in our locality are atrophies and most of these lesions are obtained as orchidectomies for therapy of prostatic cancer.

摘要

背景

睾丸是男性生殖腺,是女性卵巢的同源器官,执行着关键功能。睾丸可能出现病理状况,使这些功能减弱或完全丧失,导致临床上明显或隐匿的后遗症。本研究的目的是探讨2012年1月至2021年12月31日期间,乔斯大学教学医院经组织学诊断的睾丸疾病模式及其临床特征。

方法

本研究是对所有睾丸活检病例的回顾性分析。从科室记录中识别出所有经组织学诊断的睾丸病变,并从病历科患者文件夹中进一步获取临床资料。

结果

共进行了430例活检,其中304例(70.7%)为睾丸切除术标本。最常见的组织学诊断是睾丸萎缩,占328例(76.3%)。其次是睾丸扭转,有42例(9.8%)。炎症性疾病共36例(8.4%),其中肉芽肿性炎症占病例的52.3%。有16例(3.7%)肿瘤性疾病,均为恶性,其中6例(37.5%)为精原细胞瘤。年龄范围、平均年龄、中位数年龄和众数年龄分别为1至90岁、53.4±21.3岁、60岁和70岁。双侧睾丸切除术形式的前列腺癌治疗是手术的主要指征。

结论

我们当地大多数睾丸病变为萎缩,且大多数这些病变是作为前列腺癌治疗的睾丸切除术标本获得的。

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