Markov Daniel, Bechev Kristian I, Aleksiev Vladimir, Koev Ilian
General and Clinical Pathology, Medical University of Plovdiv, Plovdiv, BGR.
Clinical Pathology, University Hospital Pulmed, Plovdiv, BGR.
Cureus. 2024 Jun 5;16(6):e61759. doi: 10.7759/cureus.61759. eCollection 2024 Jun.
This article presents a case study of a rare convexity meningioma located in the frontal lobe of the right cerebellar hemisphere. Meningiomas comprise a substantial part of central nervous system neoplasms and are classified into benign, atypical, or anaplastic categories, each encompassing a variety of histological subtypes, among which the secretory meningioma is notably rare. A 77-year-old male presented with a clinical history of headache, impaired memory functions, an initial form of apathetic-abulic syndrome, and a single seizure, which were considered to be indicative of epileptic symptoms that had been present for several weeks. The imaging studies conducted showed a convexity tumor characterized by a rounded morphology and homogeneous contrast enhancement, positioned adjacent to the frontal lobe's cortical surface. This clinical report details the pathology of a secretory type of meningioma, which is distinguished by the atypical epithelial differentiation of meningothelial cells, resulting in hyaline fiber production. The neoplasm's anatomical accessibility permitted successful surgical resection. The tumor's position was appropriate for surgical removal, and the histological variant, along with the patient's favorable clinical course, is of particular scientific interest.
本文介绍了一例位于右小脑半球额叶的罕见凸面脑膜瘤的病例研究。脑膜瘤是中枢神经系统肿瘤的重要组成部分，分为良性、非典型或间变性类别，每类都包含多种组织学亚型，其中分泌型脑膜瘤尤为罕见。一名77岁男性患者有头痛、记忆功能受损、初始形式的淡漠-无动性缄默综合征及单次癫痫发作的临床病史，这些症状被认为提示癫痫症状已持续数周。影像学检查显示一个凸面肿瘤，形态呈圆形，对比增强均匀，位于额叶皮质表面附近。本临床报告详细阐述了分泌型脑膜瘤的病理学特征，其特点是脑膜内皮细胞的非典型上皮分化，导致透明纤维产生。肿瘤在解剖学上易于接近，从而得以成功进行手术切除。肿瘤的位置适合手术切除，其组织学变异以及患者良好的临床病程具有特殊的科学研究价值。
