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内侧颞叶异柠檬酸脱氢酶(IDH)突变型星形细胞瘤切除术后的手术腔扩张:病例说明

Surgical cavity dilatation after resection of IDH-mutated astrocytoma of the mesial temporal lobe: illustrative cases.

作者信息

Caudron Yohan, Martino Juan, Froelich Sébastien, Mandonnet Emmanuel

机构信息

Department of Neurosurgery, Lariboisière Hospital, Paris, France.

Paris Cité University, Paris, France.

出版信息

J Neurosurg Case Lessons. 2024 Jul 8;8(2). doi: 10.3171/CASE23674.

DOI:10.3171/CASE23674
PMID:38976925
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11284658/
Abstract

BACKGROUND

Space-occupying tumor bed cysts may exceptionally happen after the resection of diffuse low-grade glioma. Their mechanism and management remain debated. The authors report two cases of tumor bed cysts occurring after the resection of a left temporal diffuse low-grade glioma with two different evolutions.

OBSERVATIONS

The first patient showed a spontaneous decrease in the cyst volume and did not report any symptoms. In contrast, the second patient showed a progressive increase in the cyst volume and reported headaches and difficulties in finding words. Endoscopic cyst fenestration was performed and led to symptom relief and normalization of the surgical cavity.

LESSONS

A tumor bed cyst is a rare complication of temporal low-grade glioma resection. Its formation is due to entrapment of the choroid plexus in the temporal horn widely opened into the surgical cavity. Endoscopic cyst fenestration should be offered only in symptomatic cases. https://thejns.org/doi/10.3171/CASE23674.

摘要

背景

弥漫性低级别胶质瘤切除术后可能会罕见地出现占位性肿瘤床囊肿。其发生机制及处理方法仍存在争议。作者报告了两例左颞叶弥漫性低级别胶质瘤切除术后出现的肿瘤床囊肿,且囊肿有两种不同的演变过程。

观察结果

首例患者囊肿体积自发减小,且未出现任何症状。相比之下,第二例患者囊肿体积逐渐增大,并出现头痛及找词困难的症状。遂进行了内镜下囊肿开窗术,术后症状缓解,术腔恢复正常。

经验教训

肿瘤床囊肿是颞叶低级别胶质瘤切除术的一种罕见并发症。其形成是由于脉络丛被困于广泛开放至术腔的颞角内。仅在出现症状的情况下才应进行内镜下囊肿开窗术。https://thejns.org/doi/10.3171/CASE23674 。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/40fe/11284658/04aeb7ec3fc8/CASE23674_figure_2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/40fe/11284658/e2b71e7e9010/CASE23674_figure_1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/40fe/11284658/04aeb7ec3fc8/CASE23674_figure_2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/40fe/11284658/e2b71e7e9010/CASE23674_figure_1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/40fe/11284658/04aeb7ec3fc8/CASE23674_figure_2.jpg

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本文引用的文献

1
Postoperative Communicating Hydrocephalus Following Grade 2/3 Glioma Resection: Incidence, Timing and Risk Factors.2/3级胶质瘤切除术后交通性脑积水:发病率、发生时间及危险因素
Cancers (Basel). 2023 Jul 9;15(14):3548. doi: 10.3390/cancers15143548.
2
Extent of resection in diffuse low-grade gliomas and the role of tumor molecular signature-a systematic review of the literature.弥漫性低级别胶质瘤的切除范围及肿瘤分子特征的作用——文献系统综述
Neurosurg Rev. 2021 Jun;44(3):1371-1389. doi: 10.1007/s10143-020-01362-8. Epub 2020 Aug 7.
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Transcorticosubcortical Approach for Left Posterior Mediobasal Temporal Region Gliomas: A Case Series and Anatomic Review of Relevant White Matter Tracts.
皮质下经皮质左后侧颞叶中下部脑胶质瘤切除术:病例系列及相关白质纤维束解剖学复习
World Neurosurg. 2020 Jul;139:e737-e747. doi: 10.1016/j.wneu.2020.04.147. Epub 2020 Apr 29.
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Challenges in cerebrospinal fluid shunting in patients with glioblastoma.脑胶质母细胞瘤患者脑脊液分流的挑战。
Fluids Barriers CNS. 2018 Jun 4;15(1):16. doi: 10.1186/s12987-018-0101-x.
5
Endoscopic Visualization of an Iatrogenic Valve Mechanism: Elucidating the Pathogenesis of Postoperative Tumor Bed Cysts.医源性瓣膜机制的内镜可视化:阐明术后肿瘤床囊肿的发病机制
World Neurosurg. 2018 Jul;115:213-215. doi: 10.1016/j.wneu.2018.04.087. Epub 2018 Apr 22.
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The transcortical equatorial approach for gliomas of the mesial temporal lobe: techniques and functional outcomes.经皮质赤道入路切除颞叶内侧胶质瘤:技术与功能预后。
J Neurosurg. 2019 Mar 1;130(3):822-830. doi: 10.3171/2017.10.JNS172055.
7
Space-Occupying Tumor Bed Cysts as a Complication of Modern Treatment for High-Grade Glioma.占位性肿瘤床囊肿作为高级别胶质瘤现代治疗的一种并发症
World Neurosurg. 2017 Aug;104:509-515. doi: 10.1016/j.wneu.2017.05.019. Epub 2017 May 13.
8
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Case Rep Med. 2010;2010. doi: 10.1155/2010/634839. Epub 2010 Sep 28.
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Occurrence and therapy of space-occupying cystic lesions after brain tumor surgery.脑肿瘤手术后占位性囊性病变的发生与治疗
Zentralbl Neurochir. 2001;62(3):87-92. doi: 10.1055/s-2001-21792.