遗传性线粒体视神经病变中使用化疗的病例报告：顺铂/依托泊苷成功治疗一名患有睾丸精原细胞瘤和Leber遗传性视神经病变的男性患者
A case for the use of chemotherapy in hereditary mitochondrial optic neuropathies: Successful administration of cisplatin/etoposide in a male patient with testicular seminoma and Leber's hereditary optic neuropathy.
作者信息
Vrisakis Jean-Luc, Fraser Clare L, Shahnam Adel, Nindra Udit, Grimison Peter
机构信息
Department of Medicine Royal Prince Alfred Hospital Sydney New South Wales Australia.
Department of Medicine and Health, Save Sight Institute University of Sydney Sydney New South Wales Australia.
出版信息
Clin Case Rep. 2024 Jul 8;12(7):e9045. doi: 10.1002/ccr3.9045. eCollection 2024 Jul.
Abstract
We report on the successful use of chemotherapy for treatment of stage 2B testicular seminoma in a carrier of the Leber's hereditary optic neuropathy 11778 mitochondrial mutation. Neurotoxic chemotherapy may not prompt disease conversion.
摘要
我们报告了对一名携带Leber遗传性视神经病变11778线粒体突变的2B期睾丸精原细胞瘤患者成功使用化疗的情况。具有神经毒性的化疗可能不会促使疾病转化。
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