Liang Zi-Cong, Ouyang Hao, Song Xue-Jing, Liang Jian-Xin, Zheng Wei-Hua, Chen Jian-Jun, Yin Zheng-Gang, Chen Sha-Yan
Department of Laboratory Science, Binhaiwan Central Hospital of Dongguan, Dongguan 523905, Guangdong Province, China.
Key Laboratory of accurately etiological research on the pathogenesis of inflammation and cancer, Dongguan 523905, Guangdong Province, China.
World J Clin Cases. 2024 Jun 26;12(18):3596-3602. doi: 10.12998/wjcc.v12.i18.3596.
The bacterium , classified as a gram-negative member of the phylum Proteobacteria, is distinguished by its rarity, corrosive nature, facultative anaerobic properties, and conditional pathogenicity. It represents the sole species within its genus- ()-and can be found colonizing both human and animal oral and nasopharyngeal regions. Additionally, it occasionally inhabits the gastrointestinal or urogenital tracts. However, its slow growth rate can be attributed to its high nutritional requirements. However, there is an uneven distribution of construction and diagnostic capacity in China which poses undeniable challenges for the clinical examination and analysis of this case, especially in the basic hospitals.
Here we presented a case of empyema associated with infection in a 67-year-old male patient without any previous history of infectious diseases in our primary hospital in Dongguan district of China. The patient was admitted due to recurrent worsening cough, sputum production, and dyspnea for 3 d, which had persisted for over 20 years. Moreover, the patient experienced a one-hour episode of unconsciousness. Upon admission, immediate comprehensive examinations were conducted on the patient which subsequently led to his admission to the intensive care unit. Meanwhile, the patient presented with drowsiness and profuse sweating along with bilateral conjunctival edema observed during initiation of non-invasive ventilation, suggesting empyema. A significant amount of coffee-colored malodorous pleural fluid was drained during the procedure above and sent to the laboratory department for inspection. Finally, laboratory culture results confirmed the presence of infection in the pleural fluid sample. The patient received antimicrobial therapy until died on day 22 in the hospital.
In this report, we presented a case of empyema associated with infection. Multiple courses of morphological examination, viable culture analysis, and biochemical identification revealed its difficulties in detecting distinctive characteristics, as well as a detection model worth promoting. It's just that there were still certain deficiencies in terms of morphological assessment, biochemical identification, and drug susceptibility testing.
该细菌被归类为变形菌门的革兰氏阴性菌,其特点是罕见、具有腐蚀性、兼性厌氧特性和条件致病性。它是其属内唯一的物种(),可在人类和动物的口腔及鼻咽区域定殖。此外,它偶尔也栖息于胃肠道或泌尿生殖道。然而,其生长速度缓慢可归因于其高营养需求。然而,中国的检测和诊断能力分布不均衡,这给该病例的临床检查和分析带来了不可否认的挑战,尤其是在基层医院。
在此,我们报告了一例在中国东莞市某基层医院发生的与感染相关的脓胸病例,患者为一名67岁男性,既往无任何传染病史。患者因反复加重的咳嗽、咳痰和呼吸困难3天入院,这些症状已持续20多年。此外,患者还经历了一次长达一小时的昏迷发作。入院后,立即对患者进行了全面检查,随后将其收入重症监护病房。同时,患者出现嗜睡、多汗,在开始无创通气时观察到双侧结膜水肿,提示脓胸。在上述操作过程中引出了大量咖啡色恶臭胸腔积液,并送往检验科检查。最终,实验室培养结果证实胸腔积液样本中存在感染。患者接受了抗菌治疗,直至在医院第22天死亡。
在本报告中,我们呈现了一例与感染相关的脓胸病例。多轮形态学检查、活菌培养分析和生化鉴定揭示了其在检测独特特征方面的困难,以及一个值得推广的检测模式。只是在形态学评估、生化鉴定和药敏试验方面仍存在一定不足。