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以腹痛为表现的腰椎感染:一例病例报告及文献综述

Lumbar Spine Infection with Presented as Abdominal Pain: A Case Report and Literature Review.

作者信息

Cheng Hanwen, Tan Ni, Lu Yiwen, Wu Haoyu, Liu Zhuojie, Zhang Di, Xu Zixin, Li Chunhai

机构信息

Department of Orthopaedics, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, Guangdong Province, People's Republic of China.

Cellular & Molecular Diagnostics Center, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou, Guangdong Province, People's Republic of China.

出版信息

Infect Drug Resist. 2023 Mar 13;16:1407-1417. doi: 10.2147/IDR.S400451. eCollection 2023.

Abstract

BACKGROUND

is a part of the inherent flora on the surface of human mucosa. It usually does not cause disease unless the patient has been bitten, injured or surgically infected. Lumbar spine infection caused by usually presents with conventional symptoms such as low back pain and fever. Herein, we report a case of lumbar intervertebral space infection with presented as abdominal pain.

CASE PRESENTATION

A 38-year-old man with no medical history of note presented with abdominal pain. Initially, local doctors suspected that the patient had abdominal disease. However, abdominal diseases were ruled out and only lumbar spine infection was confirmed. Then, the patient was misdiagnosed as lumbar tuberculosis. Finally, anaerobic culture and metagenomic next-generation sequencing confirmed the , which was rarely involved in lumbar intervertebral space infection. The patient recovered after operation and antibiotic therapy.

CONCLUSION

This case indicated a rare symptom of lumbar spine infection, abdominal cramping, which is caused by . Blood culture had low sensitivity as a diagnostic method for , but lesion sample culture or metagenomic next-generation sequencing had high sensitivity for early diagnosis.

摘要

背景

是人类黏膜表面固有菌群的一部分。通常不会引发疾病,除非患者被咬伤、受伤或手术感染。由引起的腰椎感染通常表现为腰痛和发热等常见症状。在此,我们报告一例以为表现形式的腰椎间隙感染病例,其症状为腹痛。

病例介绍

一名无显著病史的38岁男性出现腹痛症状。起初,当地医生怀疑患者患有腹部疾病。然而,腹部疾病被排除,仅确诊为腰椎感染。随后,该患者被误诊为腰椎结核。最终,厌氧培养和宏基因组下一代测序确诊了,其很少累及腰椎间隙感染。患者术后经抗生素治疗康复。

结论

该病例表明腰椎感染存在一种罕见症状,即由引起的腹部绞痛。血培养作为的诊断方法敏感性较低,但病变样本培养或宏基因组下一代测序对早期诊断具有较高敏感性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/829b/10022453/29aae288e6e3/IDR-16-1407-g0001.jpg

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