Department of General Pediatrics, Tokyo Metropolitan Children's Medical Center, Tokyo, Japan.
Division of Infectious Diseases, Department of Pediatrics, Tokyo Metropolitan Children's Medical Center, Tokyo, Japan; Division of Immunology, Department of Pediatrics, Tokyo Metropolitan Children's Medical Center, Tokyo, Japan.
J Infect Chemother. 2020 May;26(5):510-512. doi: 10.1016/j.jiac.2019.12.014. Epub 2020 Jan 23.
Eikenella corrodens is a facultatively anaerobic gram-negative rod bacterium in the oropharynx and respiratory tract. It is a member of HACEK (Haemophilus spp., Aggregatibacter spp., Cardiobacterium hominis, E. corrodens, and Kingella kingae) group commonly associated with endocarditis and craniofacial infections. It is usually susceptible to penicillin, second and third-generation cephalosporins, and carbapenem, but has variable susceptibility to first-generation cephalosporin. We herein provide a description of the first case of pediatric acute dacryocystitis caused by E. corrodens. The patient did not respond to oral cephalexin and required surgical drainage followed by intravenous cefotaxime. Also provided is a brief review of the current literature.
侵蚀艾肯菌是一种兼性厌氧革兰氏阴性杆菌，存在于口咽部和呼吸道。它是 HACEK（嗜血杆菌属、Aggregatibacter 属、心杆菌属、侵蚀艾肯菌和金氏金菌）组的一员，通常与心内膜炎和头面部感染有关。它通常对青霉素、二代和三代头孢菌素以及碳青霉烯类敏感，但对一代头孢菌素的敏感性不同。本文介绍了首例由侵蚀艾肯菌引起的儿童急性泪囊炎。患儿对口服头孢氨苄反应不佳，需要手术引流，随后静脉注射头孢噻肟。同时对当前文献进行简要回顾。
