Serra Francesco, Caccialanza Riccardo, Pedrazzoli Paolo
Medical Oncology Unit, Hospital Policlinico San Matteo, Internal Medicine and Medical Therapy Department, University of Pavia, Pavia, Italy.
Nutrition and Dietetic Unit - Hospital IRCCS Policlinico San Matteo, Pavia, Italy.
Drugs Context. 2024 Jul 1;13. doi: 10.7573/dic.2024-3-4. eCollection 2024.
Scientific research has often investigated the role of diet as a risk factor for cancer development. It is well known that cancer has a multifactorial origin in which several factors are involved: genetic predisposition, dietary factors, personal habits, and infectious and environmental factors. In this Commentary, the role of diet in cancer is discussed following the scientific evidence suggesting that excessive consumption of red meat and processed foods is correlated with a greater risk of contracting cancer. Nevertheless, public health strategies on nutrition in cancer prevention are struggling to take off. The decision to pursue a healthier diet, along with a healthier lifestyle, often comes when the cancer diagnosis is made and not before. On the other hand, scientific evidence demonstrates how nutritional support is increasingly important during oncological treatments. This paper highlights how far we are still from the global adoption of a healthy and sustainable food style from a health, economic, social and environmental perspective. Additionally, it highlights the ancient vision of the role of nutrition on cancer development in which diet is seen only as a possible risk factor, underestimating the protective role in terms of cancer prevention and the modulatory one once the oncological diagnosis has been made.
科学研究经常探讨饮食作为癌症发生风险因素的作用。众所周知,癌症具有多因素起源,涉及多种因素:遗传易感性、饮食因素、个人习惯以及感染和环境因素。在本评论中,我们将根据科学证据讨论饮食在癌症中的作用,这些证据表明过量食用红肉和加工食品与患癌风险增加相关。然而,癌症预防方面的公共卫生营养策略仍难以推行。追求更健康饮食以及更健康生活方式的决定,往往是在癌症确诊时才做出,而不是在此之前。另一方面,科学证据表明营养支持在肿瘤治疗期间越来越重要。本文从健康、经济、社会和环境角度强调了我们在全球采用健康和可持续饮食方式方面仍有很大差距。此外,它还强调了关于营养在癌症发生中作用的古老观点,即饮食仅被视为一种可能的风险因素,而低估了其在癌症预防方面的保护作用以及肿瘤诊断后对病情的调节作用。