Rauf Sameer A, Ahmed Rubayyi, Hussain Tooba, Saad Muhammad, Shah Hussain H, Jamalvi Syed A, Yogeeta Fnu, Devi Muskan, Subash Arun, Gul Maryam, Ahmed Shaheer, Haque Md Ariful
Liaquat National Medical College.
Dow University of Health Sciences, Karachi, Pakistan.
Ann Med Surg (Lond). 2024 May 23;86(7):4255-4261. doi: 10.1097/MS9.0000000000002218. eCollection 2024 Jul.
This review provides a comprehensive overview of the therapeutic and diagnostic implications of fluorescence imaging in neurosurgery. Fluorescence imaging has become a valuable intraoperative visualization and guidance tool, facilitating precise surgical interventions. The therapeutic role of fluorescence is examined, including its application in photodynamic therapy and tumor-targeted therapy. It also explores its diagnostic capabilities in tumor detection, margin assessment, and blood-brain barrier evaluation. Drawing from clinical and preclinical studies, the review underscores the growing evidence supporting the efficacy of fluorescence imaging in neurosurgical practice. Furthermore, it discusses current limitations and future directions, emphasizing the potential for emerging technologies to enhance the utility and accessibility of fluorescence imaging, ultimately improving patient outcomes in neurosurgery.
本综述全面概述了荧光成像在神经外科手术中的治疗和诊断意义。荧光成像已成为一种有价值的术中可视化和引导工具，有助于进行精确的手术干预。文中探讨了荧光的治疗作用，包括其在光动力疗法和肿瘤靶向治疗中的应用。还研究了其在肿瘤检测、边界评估和血脑屏障评估方面的诊断能力。基于临床和临床前研究，本综述强调了越来越多的证据支持荧光成像在神经外科实践中的有效性。此外，讨论了当前的局限性和未来方向，强调新兴技术有潜力提高荧光成像的实用性和可及性，最终改善神经外科手术患者的治疗效果。
