Alshahrani Mona, Almalki Laila Zawan, Hasoosah Noura Abdullah, Alahmari Alhanouf Hussein, Alqahtani Alya Musfer, Alqahtani Amjad Ali, Al Muarfaj Afrah Mohammed, Al Ghaseb Lamia Saeed, Alkahtani Faten Saad, Alsharif Raghd Yahya
Faculty of Medicine, King Khalid University, Abha.
College of Medicine, King Khalid University, Abha, Saudi Arabia.
Ann Med Surg (Lond). 2024 Jan 26;86(7):3909-3916. doi: 10.1097/MS9.0000000000001755. eCollection 2024 Jul.
Chronic kidney disease (CKD) is a major health concern in Saudi Arabia. The prevalence of CKD and associated risk factors in Saudi Arabia's general population are not efficiently studied. The goal of this research is to determine the prevalence rate of CKD in the ASIR region and its associated epidemiological risk factors.
This is a cross-sectional study that used a comprehensive direct questionnaire to collect data on CKD prevalence and risk factors in the ASIR region of Saudi Arabia. The study was carried out in different age groups. Demographic characteristics, presence of CKD, and associated factors such as a history of acute kidney disease, obstructive sleep apnoea, family history, history of non-steroid anti-inflammatory drugs (NSAID), smoking status, comorbidities, and history of periodontal diseases were asked. The survey tool was validated through a pilot study, and a statistical value of 0.05 was considered significant.
A total of 967 participants were included in the study, with a CKD prevalence rate of 1.9%. Sex, history of acute kidney disease, obstructive sleep apnoea, family history of kidney disease, smoking, diabetes, peptic ulcer disease, hypertension and hyperlipidemia were commonly found to be associated with CKD. A binary logistic regression model was carried out to assess the risk factors for CKD. Sex, history of acute kidney disease, family history of kidney disease, obstructive sleep apnoea, smoking status, peptic ulcer, diabetes, hypertension, hyperlipidemia, hypertension and diabetes, two or more comorbidities and NSAID use had an increased risk of CKD.
Sex, history of acute kidney disease, obstructive sleep apnoea, family history, smoking, diabetes, hypertension, peptic ulcer, hyperlipidemia, multi-comorbidity, and use of NSAIDs are all associated with an increased risk of CKD. The prevalence of CKD in this study is comparatively lower when compared to other regions in Saudi Arabia.
慢性肾脏病（CKD）是沙特阿拉伯主要的健康问题。沙特阿拉伯普通人群中CKD的患病率及相关危险因素尚未得到充分研究。本研究的目的是确定阿西尔地区CKD的患病率及其相关的流行病学危险因素。
这是一项横断面研究，使用综合直接问卷收集沙特阿拉伯阿西尔地区CKD患病率和危险因素的数据。该研究在不同年龄组中进行。询问了人口统计学特征、CKD的存在情况以及相关因素，如急性肾病史、阻塞性睡眠呼吸暂停、家族史、非甾体抗炎药（NSAID）史、吸烟状况、合并症和牙周病史。调查工具通过预试验进行了验证，统计学值0.05被认为具有显著性。
共有967名参与者纳入研究，CKD患病率为1.9%。性别、急性肾病史、阻塞性睡眠呼吸暂停、肾病家族史、吸烟、糖尿病、消化性溃疡病、高血压和高脂血症通常被发现与CKD有关。进行二元逻辑回归模型以评估CKD的危险因素。性别、急性肾病史、肾病家族史、阻塞性睡眠呼吸暂停、吸烟状况、消化性溃疡、糖尿病、高血压、高脂血症、高血压和糖尿病、两种或更多合并症以及使用NSAID会增加患CKD的风险。
性别、急性肾病史、阻塞性睡眠呼吸暂停、家族史、吸烟、糖尿病、高血压、消化性溃疡、高脂血症、多重合并症以及使用NSAIDs均与CKD风险增加有关。与沙特阿拉伯其他地区相比，本研究中CKD的患病率相对较低。
