Hegde Vibha Rahul, Hegde Sanitra Rahul, Fanibunda Ushaina Eruch, Vartak Meghana Aditya
Department of Conservative Dentistry and Endodontics, YMT Dental College and Hospital, Navi Mumbai, Maharashtra, India.
J Conserv Dent Endod. 2025 Mar;28(3):211-221. doi: 10.4103/JCDE.JCDE_8_25. Epub 2025 Mar 3.
To compare the postoperative pain and healing following obturation with calcium silicate and bioactive glass-based sealers to epoxy resin sealers.
A systematic search (2018-2024) was conducted using PubMed, Cochrane, and Google Scholar, following the Preferred Reporting Items for Systematic Reviews and Meta-analyses guidelines (PRISMA). Risk of bias (RoB) was assessed using Cochrane RoB 2 tool and quality was evaluated using GRADE. Twenty-three studies were included for qualitative analysis and 11 for quantitative analysis, including meta-analysis for bioactive glass and epoxy resin-based sealers.
Meta-analysis revealed no significant difference in pain occurrence between groups at 24 h, 48 h, and 7 days. Similarly, for bioactive glass sealer, no significant difference in pain occurrence was observed at 24 h, 48 h, and 7 days.
Calcium-silicate-based sealers showed comparable and satisfactory results to epoxy resin sealers regarding postoperative pain incidence and intensity. In addition, they facilitated improved healing of periapical tissues. Notably, bioactive glass-based sealer also demonstrated exceptional properties, offering enhanced benefits.
比较硅酸钙和生物活性玻璃基封闭剂与环氧树脂封闭剂根管充填后的术后疼痛及愈合情况。
按照系统评价和Meta分析的首选报告项目（PRISMA）指南，于2018年至2024年利用PubMed、Cochrane和谷歌学术进行系统检索。采用Cochrane偏倚风险2工具评估偏倚风险，并使用GRADE评估质量。纳入23项研究进行定性分析，11项进行定量分析，包括生物活性玻璃和环氧树脂基封闭剂的Meta分析。
Meta分析显示，两组在术后24小时、48小时和7天时疼痛发生率无显著差异。同样，对于生物活性玻璃封闭剂，在术后24小时、48小时和7天时疼痛发生率也无显著差异。
在术后疼痛发生率和强度方面，硅酸钙基封闭剂与环氧树脂封闭剂的效果相当且令人满意。此外，它们有助于促进根尖周组织的愈合。值得注意的是，生物活性玻璃基封闭剂也表现出优异的性能，具有更多益处。
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