College of Arts and Sciences, Department of Biological and Environmental Science, Qatar.
Centre for Advanced Materials, Qatar University, Qatar.
Life Sci. 2024 Sep 1;352:122899. doi: 10.1016/j.lfs.2024.122899. Epub 2024 Jul 9.
This comprehensive review provides an in-depth analysis of how nanotechnology has revolutionized cancer theragnostic, which combines diagnostic and therapeutic methods to customize cancer treatment. The study examines the unique attributes, uses, and difficulties linked to different types of nanoparticles, including gold, iron oxide, silica, Quantum dots, Carbon nanotubes, and liposomes, in the context of cancer treatment. In addition, the paper examines the progression of nanotheranostics, emphasizing its uses in precise medication administration, photothermal therapy, and sophisticated diagnostic methods such as MRI, CT, and fluorescence imaging. Moreover, the article highlights the capacity of nanoparticles to improve the effectiveness of drugs, reduce the overall toxicity in the body, and open up new possibilities for treating cancer by releasing drugs in a controlled manner and targeting specific areas. Furthermore, it tackles concerns regarding the compatibility of nanoparticles and their potential harmful effects, emphasizing the significance of continuous study to improve nanotherapeutic methods for use in medical treatments. The review finishes by outlining potential future applications of nanotechnology in predictive oncology and customized medicine.
这篇全面的综述深入分析了纳米技术如何彻底改变癌症诊治一体化,即将诊断和治疗方法相结合以定制癌症治疗。该研究在癌症治疗的背景下,考察了不同类型的纳米粒子(包括金、氧化铁、二氧化硅、量子点、碳纳米管和脂质体)的独特属性、用途和困难。此外,本文还探讨了纳米诊治学的进展,强调了其在精确药物管理、光热疗法以及磁共振成像(MRI)、计算机断层扫描(CT)和荧光成像等复杂诊断方法中的应用。此外,文章还强调了纳米粒子提高药物疗效、降低全身毒性以及通过控制药物释放和靶向特定区域为癌症治疗开辟新途径的能力。此外,还解决了纳米粒子的兼容性和潜在有害影响的问题,强调了持续研究以改善用于医疗的纳米治疗方法的重要性。综述最后概述了纳米技术在预测肿瘤学和定制医学方面的潜在未来应用。