El-Mallul Ahmed, Tomasiuk Ryszard, Pieńkowski Tadeusz, Kowalska Małgorzata, Hasan Dilawar, Kostrzewa Marcin, Czerwonka Dominik, Sado Aleksandra, Rogowska Wiktoria, Zubrzycki Igor Z, Wiacek Magdalena
Faculty of Medical Sciences and Health Sciences, Radom University, Chrobrego 27, 26-600 Radom, Poland.
Libyan Academy for Postgraduate Studies, Sidi Abdoljalil Road 3, Janzur 40225, Libya.
Nanomaterials (Basel). 2025 Aug 6;15(15):1200. doi: 10.3390/nano15151200.
Nanotechnology offers innovative methodologies for enhancing the diagnosis and treatment of ovarian cancer by utilizing specialized nanoparticles. The utilization of nanoparticles offers distinct advantages, specifically that these entities enhance the bioavailability of therapeutic agents and facilitate the targeted delivery of pharmacological agents to neoplastic cells. A diverse array of nanoparticles, including but not limited to liposomes, dendrimers, and gold nanoparticles, function as proficient carriers for drug delivery. Nevertheless, notwithstanding the auspicious potential of these applications, challenges pertaining to toxicity, biocompatibility, and the necessity for comprehensive clinical evaluations pose considerable barriers to the widespread implementation of these technologies. The incorporation of nanotechnology into clinical practice holds the promise of significantly transforming the management of ovarian cancer, offering novel diagnostic tools and therapeutic strategies that enhance patient outcomes and prognoses. In summary, the deployment of nanotechnology in the context of ovarian cancer epitomizes a revolutionary paradigm in medical science, amalgamating sophisticated materials and methodologies to enhance both diagnostic and therapeutic outcomes. Continued research and development endeavors are essential to fully realize the extensive potential of these innovative solutions and address the existing challenges associated with their application in clinical settings.
纳米技术提供了创新方法,通过利用特殊的纳米颗粒来加强卵巢癌的诊断和治疗。纳米颗粒的应用具有显著优势,具体而言,这些实体提高了治疗剂的生物利用度,并促进了药理剂向肿瘤细胞的靶向递送。各种各样的纳米颗粒,包括但不限于脂质体、树枝状大分子和金纳米颗粒,都可作为高效的药物递送载体。然而,尽管这些应用具有良好潜力,但与毒性、生物相容性以及全面临床评估的必要性相关的挑战,对这些技术的广泛应用构成了重大障碍。将纳米技术纳入临床实践有望显著改变卵巢癌的管理方式,提供新的诊断工具和治疗策略,从而改善患者的治疗效果和预后。总之,在卵巢癌领域应用纳米技术是医学科学中的一种革命性范例,它融合了先进材料和方法以提高诊断和治疗效果。持续的研发工作对于充分实现这些创新解决方案的巨大潜力以及解决其在临床应用中存在的相关挑战至关重要。