Li Shu-Han, Yang Cai-Xiu, Xing Xiao-Ming, Gao Xiang-Ru, Lu Zhao-Yu, Ji Qiu-Xia
Department of Periodontology, The Affiliated Hospital of Qingdao University, Qingdao 266003, Shandong Province, China.
Department of Periodontology, School of Stomatology of Qingdao University, Qingdao 266000, Shandong Province, China.
World J Clin Cases. 2024 Jul 6;12(19):3985-3994. doi: 10.12998/wjcc.v12.i19.3985.
Myeloid sarcoma (MS), also referred to as granulocytic sarcoma or chloroma, is a rare type of extramedullary malignant tumor. MS comprises primitive granulocytic precursor cells that play a key role in the early stages of white blood cell development. Notably, the occurrence of this tumor in the gingiva is rare.
The present study reported the case of MS with gingival swelling in the maxillary region, with aleukemic presentation in a 32-year-old male patient. Following two courses of chemotherapy, computed tomography of the region demonstrated complete clearance of the tumor. At the 12-month follow-up appointment, the patient was in a stable condition with the absence of progression. The etiology, clinical features, diagnosis, and relevant treatment of MS are discussed in the present study.
Diagnosis of MS may be confirmed following histological and immunohistochemical examinations.
髓系肉瘤(MS),也称为粒细胞肉瘤或绿色瘤,是一种罕见的髓外恶性肿瘤。MS由原始粒细胞前体细胞组成,这些细胞在白细胞发育的早期阶段起关键作用。值得注意的是,这种肿瘤发生在牙龈的情况很少见。
本研究报告了一名32岁男性患者上颌区域牙龈肿胀的髓系肉瘤病例,表现为无白血病。经过两个疗程的化疗后,该区域的计算机断层扫描显示肿瘤完全清除。在12个月的随访预约中,患者病情稳定,无进展。本研究讨论了髓系肉瘤的病因、临床特征、诊断及相关治疗。
髓系肉瘤的诊断可通过组织学和免疫组化检查来确诊。