Martínez Nieto Melissa, González Gómez Luis Antonio, Gómez Mireles Juan Carlos, Lomelí Martínez Sarah Monserrat
Department of Integrated Dentistry Clinics, Centro Universitario de Ciencias de la Salud, Universidad de Guadalajara, Guadalajara 44340, Mexico.
Department of Medical and Life Sciences, Centro Universitario de la Ciénega, Universidad de Guadalajara, Ocotlán 47810, Mexico.
World J Clin Cases. 2024 Nov 16;12(32):6526-6533. doi: 10.12998/wjcc.v12.i32.6526.
Myeloid sarcoma (MS) is a rare neoplasm characterized by the proliferation of immature myeloid precursor cells outside the bone marrow. The pathogenesis of MS is complex and not completely understood. Moreover, it develops in any extramedullary site of the body. In this editorial, we discuss the article published by Li , which presents a clinical case involving a 32-year-old man who exhibited gingival inflammation in the maxillary region. It was initially diagnosed as periodontal disease. However, clinical evaluation revealed a firm, grayish-white mass which underscored the need for comprehensive diagnostics to distinguish MS from other oral conditions. This article emphasizes the different clinical presentations of similar case studies in the literature, and highlights the difficulty in diagnosing oral MS due to its rarity and variability in clinical manifestation. The treatment of MS depends on the clinical presentation, tumor location, and the patient's response to conventional therapies. The various therapeutic options currently available are analyzed and discussed. Early intervention and multidisciplinary management are crucial for improving treatment outcomes. Increased awareness and education about the various clinical presentations of MS lead to earlier diagnosis and timely treatment, thereby enhancing patients' survival and quality of life. Continued research is essential for optimizing therapeutic strategies and addressing the challenges presented by this rare neoplasm.
髓系肉瘤（MS）是一种罕见的肿瘤，其特征是骨髓外未成熟髓系前体细胞增殖。MS的发病机制复杂，尚未完全明确。此外，它可发生于身体的任何髓外部位。在这篇社论中，我们讨论了李发表的文章，该文章介绍了一个临床病例，涉及一名32岁男性，其上颌区域出现牙龈炎症。最初被诊断为牙周病。然而，临床评估发现了一个质地坚硬、灰白色的肿块，这凸显了进行全面诊断以将MS与其他口腔疾病区分开来的必要性。本文强调了文献中类似病例研究的不同临床表现，并强调了由于口腔MS的罕见性和临床表现的变异性而导致诊断困难。MS的治疗取决于临床表现、肿瘤位置以及患者对传统疗法的反应。目前对各种可用治疗方案进行了分析和讨论。早期干预和多学科管理对于改善治疗效果至关重要。提高对MS各种临床表现的认识和教育可实现早期诊断和及时治疗，从而提高患者的生存率和生活质量。持续研究对于优化治疗策略和应对这种罕见肿瘤带来的挑战至关重要。
