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单侧泪液缺乏作为梅克尔腔肿瘤的首发症状。

Unilateral alacrimia as a presenting symptom of Meckel's cave tumour.

作者信息

López Miñarro Ignacio Manuel, Prieto Domínguez Laura, Asensio-Sánchez Víctor Manuel

机构信息

Hospital Clínico Universitario, Ophthalmology Department, Valladolid, Spain.

出版信息

GMS Ophthalmol Cases. 2024 Jun 25;14:Doc09. doi: 10.3205/oc000241. eCollection 2024.

DOI:10.3205/oc000241
PMID:38994473
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11238642/
Abstract

Meckel's cave tumour, a rare benign tumour originating from the Schwann cells surrounding the trigeminal nerve within the Meckel's cave region, can present with a variety of clinical manifestations. We report a case of a 44-year-old male patient who presented with symptoms of tear deficiency, including dryness, ocular discomfort, and blurred vision. Diagnostic evaluation revealed the presence of a Meckel's cave tumour harming the trigeminal nerve, leading to alacrimia. This case highlights the association between Meckel's cave tumour and tear deficiency disorders.

摘要

梅克尔腔肿瘤是一种罕见的良性肿瘤，起源于梅克尔腔内三叉神经周围的施万细胞，可表现出多种临床表现。我们报告一例44岁男性患者，其出现泪液缺乏症状，包括眼干、眼部不适和视力模糊。诊断评估发现存在一个损害三叉神经的梅克尔腔肿瘤，导致泪液分泌不足。该病例突出了梅克尔腔肿瘤与泪液缺乏症之间的关联。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2997/11238642/f9e335514acb/OC-14-09-g-002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2997/11238642/7f6c7504bc4f/OC-14-09-g-001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2997/11238642/f9e335514acb/OC-14-09-g-002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2997/11238642/7f6c7504bc4f/OC-14-09-g-001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2997/11238642/f9e335514acb/OC-14-09-g-002.jpg

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本文引用的文献

1
Congenital unilateral absence of the lacrimal gland combined with lipoma. A rare case of unilateral congenital alacrima.先天性单侧泪腺缺如合并脂肪瘤。单侧先天性无泪症的罕见病例。
Arch Soc Esp Oftalmol (Engl Ed). 2021 Jan;96(1):48-51. doi: 10.1016/j.oftal.2020.05.027. Epub 2020 Jun 27.
2
New Onset Alacrima as a Presenting Feature of a Skull Base Chondrosarcoma.新发生的泪溢作为颅底软骨肉瘤的首发表现。
Ophthalmic Plast Reconstr Surg. 2020 Nov/Dec;36(6):e154-e156. doi: 10.1097/IOP.0000000000001683.
3
Ectodermal dysplasias: Classification and organization by phenotype, genotype and molecular pathway.
外胚层发育不全：按表型、基因型和分子途径分类和组织。
Am J Med Genet A. 2019 Mar;179(3):442-447. doi: 10.1002/ajmg.a.61045. Epub 2019 Jan 31.
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Isolated bilateral congenital lacrimal gland agenesis - Report of two cases.孤立性双侧先天性泪腺发育不全——两例报告
Saudi J Ophthalmol. 2017 Oct-Dec;31(4):257-259. doi: 10.1016/j.sjopt.2017.04.008. Epub 2017 May 3.
5
Surgical Management of Tumors Involving Meckel's Cave and Cavernous Sinus: Role of an Extended Middle Fossa and Lateral Sphenoidectomy Approach.累及梅克尔腔和海绵窦肿瘤的外科治疗：扩大中颅窝和外侧蝶骨切除术的作用
Otol Neurotol. 2018 Jan;39(1):82-91. doi: 10.1097/MAO.0000000000001602.
6
Unilateral Alacrima as a Presenting Symptom of Nasopharyngeal Carcinoma.单侧无泪作为鼻咽癌的首发症状
Ophthalmic Plast Reconstr Surg. 2017 Mar/Apr;33(2):e41-e42. doi: 10.1097/IOP.0000000000000714.