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用于细菌鉴定和分类学的单克隆抗体:1985年及以后。

Monoclonal antibodies for bacterial identification and taxonomy: 1985 and beyond.

作者信息

Conway de Macario E, Macario A J

出版信息

Clin Lab Med. 1985 Sep;5(3):531-44.

PMID:3899480
Abstract

Contemporary bacterial serology relevant to medicine involves poly- and monoclonal antibodies to study pathogenic bacteria and nonpathogenic organisms useful in controlling infectious diseases. Monoclonal antibody applications include immunodiagnostics, prophylaxis and serotherapy, and microbial biotechnology and molecular immunochemistry. If used in parallel with antisera, the analytic potential of monoclonal antibodies is better realized. However, the entire range of advantages from the use of monoclonal antibodies can only be attained if the antibodies are well characterized.

摘要

当代与医学相关的细菌血清学涉及多克隆抗体和单克隆抗体,用于研究病原菌以及对控制传染病有用的非病原菌。单克隆抗体的应用包括免疫诊断、预防和血清疗法,以及微生物生物技术和分子免疫化学。如果与抗血清并行使用,单克隆抗体的分析潜力能得到更好发挥。然而,只有当抗体得到充分表征时,使用单克隆抗体的所有优势才能得以实现。

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