Sommer Natascha, Franzen Klaas, Andreas Stefan, Pankow Wulf, Kunstmann Wilfried, Hanewinkel Reiner
Medizinische Klinik II, Excellence Cluster Cardio-Pulmonary Institute (CPI), Universities of Giessen and Marburg Lung Center (UGMLC), Mitglied des Deutschen Zentrums für Lungenforschung (DZL), Justus-Liebig-Universität Gießen.
Universitätsklinikum Schleswig-Holstein, Medizinische Klinik III, Pneumologie, Campus Lübeck, Airway Research Center North (ARCN), Deutsches Zentrum für Lungenforschung (DZL), Lübeck/Großhansdorf.
Laryngorhinootologie. 2025 May;104(5):288-295. doi: 10.1055/a-2341-0544. Epub 2024 Jul 12.
Almost all e-cigarettes contain flavourings that make the product more attractive. In the evaluation of e-cigarettes on health, flavors have so far played a subordinate role.Selective literature search in PubMed, supplemented by legal regulations on the use of flavors in e-cigarettes.Flavors make it easier to start using e-cigarettes and have a consumption-promoting effect. Deeper inhalation increases nicotine uptake and the absorption of toxic substances from the e-cigarette liquid. For some flavors, pathological effects have been demonstrated in addition to other toxic components of the e-cigarette. To date, no toxicological analyses are available for the vast majority of flavors contained in e-cigarettes.The proven consumption-promoting effect and the health risks that can be extrapolated from preclinical data are significant for the political discussion of a ban on flavors for e-cigarettes, analogous to the ban on flavors in tobacco products already in force.
几乎所有电子烟都含有使产品更具吸引力的调味剂。在电子烟对健康的评估中,调味剂迄今为止一直发挥着次要作用。在PubMed中进行选择性文献检索,并辅以有关电子烟中调味剂使用的法律法规。调味剂使开始使用电子烟变得更容易,并具有促进消费的作用。更深的吸入会增加尼古丁的摄入量以及电子烟液中有毒物质的吸收。对于某些调味剂,除了电子烟的其他有毒成分外,还已证明其具有病理作用。迄今为止,对于电子烟中包含的绝大多数调味剂尚无毒理学分析。已证实的促进消费作用以及可从临床前数据推断出的健康风险,对于电子烟调味剂禁令的政治讨论具有重要意义,这类似于已经实施的烟草制品调味剂禁令。