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澳大利亚畜牧业中的疼痛缓解干预措施:动物福利与疼痛持续时间综述

Pain Relief Interventions in Australian Livestock Husbandry: A Review of Animal Welfare and Pain Duration.

作者信息

Metcalf Lee, Lomax Sabrina, Van der Saag Dominique, Garg Sanjay, White Peter J

机构信息

School of Veterinary Science, University of Sydney, Camperdown, NSW 2006, Australia.

School of Life and Environmental Sciences, University of Sydney, Camperdown, NSW 2006, Australia.

出版信息

Animals (Basel). 2024 Jun 27;14(13):1901. doi: 10.3390/ani14131901.

DOI:10.3390/ani14131901
PMID:38998013
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11240665/
Abstract

In veterinary medicine and livestock production, ensuring good animal husbandry is vital for the physical and emotional wellbeing of animals under our care. Pain poses challenges for assessment and mitigation, especially in species unable to express pain overtly. This review examines current pain mitigation interventions in routine husbandry, focuses on the duration of pain after procedures and implications for animal welfare. Pain behaviours have been observed for days or weeks after regular husbandry procedures, and many studies have noted pain-related behaviour persisting until study finalisation, suggesting potential undocumented pain beyond study completion. Current products registered in Australia for pain mitigation in livestock primarily target immediate pain associated with procedures. The future of pain relief in livestock demands longer-acting solutions to address post-procedural pain adequately. Providing pain relief for at least 72 h post surgery is recommended, but current products require retreatment intervals to achieve this, posing practical challenges, especially in livestock. Methods of pain relief provision, such as voluntary consumption of medicated feed, transdermal medication delivery and long-acting formulations offer potential solutions for prolonged pain relief, with research ongoing in these areas. There is a need for further research and development of longer-acting pain relief to ensure optimal welfare of livestock.

摘要

在兽医学和畜牧生产中,确保良好的畜牧管理对于我们所照料动物的身心健康至关重要。疼痛给评估和缓解带来了挑战,尤其是在无法明显表达疼痛的物种中。本综述考察了常规畜牧管理中当前的疼痛缓解干预措施,重点关注手术后疼痛的持续时间及其对动物福利的影响。在常规畜牧程序后的数天或数周内都观察到了疼痛行为,许多研究指出与疼痛相关的行为一直持续到研究结束,这表明在研究完成后可能存在未记录的疼痛。目前在澳大利亚注册用于减轻牲畜疼痛的产品主要针对与手术相关的即时疼痛。牲畜疼痛缓解的未来需要长效解决方案来充分解决术后疼痛。建议在手术后至少72小时提供疼痛缓解,但目前的产品需要重复给药间隔才能达到这一效果,这带来了实际挑战,尤其是在牲畜身上。提供疼痛缓解的方法,如自愿食用加药饲料、透皮给药和长效制剂,为延长疼痛缓解提供了潜在的解决方案,这些领域的研究正在进行。需要进一步研发长效疼痛缓解方法,以确保牲畜的最佳福利。