Department of Reproductive Medicine, KK Women's and Children's Hospital, 100 Bukit Timah Road, Singapore 229899, Singapore.
Duke NUS Medical School, 8 College Road, Singapore 169857, Singapore.
Nutrients. 2024 Jul 8;16(13):2172. doi: 10.3390/nu16132172.
This study examines relationships between breastfeeding practices and postpartum weight retention (PPWR) at 6 and 12 months postpartum among 379 first-time mothers participating in a clinical trial in Singapore. We categorized feeding modes at 6 months into exclusive breastfeeding, mixed feeding, and exclusive formula feeding. Participants were analyzed in two groups based on their PPWR assessment at 6 and 12 months postpartum, with complete datasets available for each assessment. We calculated PPWR by subtracting pre-pregnancy weight from self-reported weight at 6 and 12 months postpartum, defining substantial PPWR as ≥5 kg retention. Modified Poisson regression models adjusted for potential confounders were performed. At 6 and 12 months, 35% ( = 132/379) and 31% ( = 109/347) of women experienced substantial PPWR, respectively. Compared to exclusive breastfeeding, mixed feeding (risk ratio 1.85; 95% confidence interval 1.15, 2.99) and exclusive formula feeding (2.11; 1.32, 3.28) were associated with a higher risk of substantial PPWR at 6 months. These associations were slightly attenuated at 12 months and appeared stronger in women with pre-pregnancy overweight or obesity. This study suggests that breastfeeding by 6 months postpartum may help mitigate PPWR, particularly with exclusive breastfeeding. It also draws attention to targeted interventions to promote breastfeeding among women with overweight or obesity.
本研究考察了 379 名首次参与新加坡临床试验的母亲产后 6 个月和 12 个月时的母乳喂养方式与产后体重滞留(PPWR)之间的关系。我们将 6 个月时的喂养方式分为纯母乳喂养、混合喂养和纯配方奶喂养。根据产后 6 个月和 12 个月的 PPWR 评估结果,将参与者分为两组,两组均有完整的数据。我们通过从产后 6 个月和 12 个月时的自我报告体重中减去孕前体重来计算 PPWR,将≥5kg 的体重滞留定义为大量 PPWR。采用调整了潜在混杂因素的修正泊松回归模型进行分析。在产后 6 个月和 12 个月时,分别有 35%(=132/379)和 31%(=109/347)的女性经历了大量 PPWR。与纯母乳喂养相比,混合喂养(风险比 1.85;95%置信区间 1.15,2.99)和纯配方奶喂养(2.11;1.32,3.28)与产后 6 个月时大量 PPWR 的风险增加相关。这些关联在产后 12 个月时略有减弱,并且在孕前超重或肥胖的女性中更为明显。本研究表明,产后 6 个月内母乳喂养可能有助于减轻 PPWR,特别是纯母乳喂养。它还提请注意针对超重或肥胖女性的母乳喂养促进干预措施。