Laboratory of Innovative Toxicological Research and Analyzes, Institute of Medical Sciences, Medical College, Rzeszów University, Al. mjr. W. Kopisto 2a, 35-959 Rzeszów, Poland.
Department of Regulatory and Forensic Toxicology, Institute of Medical Expertises, ul. Aleksandrowska 67/93, 91-205 Łódź, Poland.
Int J Mol Sci. 2024 Jun 23;25(13):6884. doi: 10.3390/ijms25136884.
Raman spectroscopy and Fourier transform infrared (FTIR) spectroscopy are powerful analytical techniques widely used separately in different fields of study. Integrating these two powerful spectroscopic techniques into one device represents a groundbreaking advance in multimodal imaging. This new combination which merges the molecular vibrational information from Raman spectroscopy with the ability of FTIR to study polar bonds, creates a unique and complete analytical tool. Through a detailed examination of the microscope's operation and case studies, this article illustrates how this integrated analytical instrument can provide more thorough and accurate analysis than traditional methods, potentially revolutionising analytical sample characterisation. This article aims to present the features and possible uses of a unified instrument merging FTIR and Raman spectroscopy for multimodal imaging. It particularly focuses on the technological progress and collaborative benefits of these two spectroscopic techniques within the microscope system. By emphasising this approach's unique benefits and improved analytical capabilities, the authors aim to illustrate its applicability in diverse scientific and industrial sectors.
拉曼光谱和傅里叶变换红外(FTIR)光谱是两种强大的分析技术,在不同的研究领域中被广泛应用。将这两种强大的光谱技术集成到一个设备中,代表了多模态成像领域的一项突破性进展。这种新的组合将拉曼光谱的分子振动信息与 FTIR 研究极性键的能力相结合,创建了一个独特而完整的分析工具。通过详细检查显微镜的操作和案例研究,本文说明了这种集成分析仪器如何比传统方法提供更全面、更准确的分析,有可能彻底改变分析样品的特性。本文旨在介绍将 FTIR 和拉曼光谱合并为多模态成像的统一仪器的特点和可能用途。它特别侧重于显微镜系统中这两种光谱技术的技术进步和协作优势。通过强调这种方法的独特优势和改进的分析能力,作者旨在说明它在各个科学和工业领域的适用性。