Zhao Jinxing, Liu Xianggui, Pu Xuelian, Shen Zetong, Xu Wenqiang, Yang Jian
Key Laboratory of Advanced Packaging Materials and Technology of Hunan Province, Hunan University of Technology, Zhuzhou 412007, China.
National & Local Joint Engineering Research Center for Advanced Packaging Material and Technology, Hunan University of Technology, Zhuzhou 412007, China.
Polymers (Basel). 2024 Jun 28;16(13):1846. doi: 10.3390/polym16131846.
Porous membrane technology has garnered significant attention in the fields of separation and biology due to its remarkable contributions to green chemistry and sustainable development. The porous membranes fabricated from polylactic acid (PLA) possess numerous advantages, including a low relative density, a high specific surface area, biodegradability, and excellent biocompatibility. As a result, they exhibit promising prospects for various applications, such as oil-water separation, tissue engineering, and drug release. This paper provides an overview of recent research advancements in the fabrication of PLA membranes using electrospinning, the breath-figure method, and the phase separation method. Firstly, the principles of each method are elucidated from the perspective of pore formation. The correlation between the relevant parameters and pore structure is discussed and summarized, subsequently followed by a comparative analysis of the advantages and limitations of each method. Subsequently, this article presents the diverse applications of porous PLA membranes in tissue engineering, oil-water separation, and other fields. The current challenges faced by these membranes, however, encompass inadequate mechanical strength, limited production efficiency, and the complexity of pore structure control. Suggestions for enhancement, as well as future prospects, are provided accordingly.
多孔膜技术因其对绿色化学和可持续发展的卓越贡献，在分离和生物学领域备受关注。由聚乳酸（PLA）制成的多孔膜具有诸多优点，包括相对密度低、比表面积高、可生物降解以及优异的生物相容性。因此，它们在油水分离、组织工程和药物释放等各种应用中展现出广阔的前景。本文综述了近年来利用静电纺丝法、呼吸图案法和相分离法制备聚乳酸膜的研究进展。首先，从孔形成的角度阐明了每种方法的原理。讨论并总结了相关参数与孔结构之间的关系，随后对每种方法的优缺点进行了比较分析。接着，本文介绍了多孔聚乳酸膜在组织工程、油水分离等领域的多种应用。然而，这些膜目前面临的挑战包括机械强度不足、生产效率有限以及孔结构控制的复杂性。相应地提供了改进建议以及未来展望。
