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[肾移植中输尿管-输尿管吻合术重建尿路连续性。附135例报告]

[Re-establishment of urinary continuity by uretero-ureterostomy in renal transplantation. Apropos of 135 cases].

作者信息

Guiter J, Cuenant E, Mourad G, Averous M, Corcos J, Navratil H, Mion C

出版信息

J Urol (Paris). 1985;91(1):27-32.

PMID:3900225
Abstract

Uretero-ureteral anastomosis was performed in 135 patients (40 women and 95 men) during kidney transplantation using either cadaver (120 cases) or living donor (15 cases) organs. The ureter of the retained kidney was linked proximal to the transplantation, whether or not there had been previous contemporary nephrectomy. Results were highly interesting: no mortality, no need to remove graft for urinary complications and no ureteral anastomotic stenosis. Urological complications were absent in 108 cases (80%) while 17 cases (12.6%) developed a urinary fistula, only 5 of which required surgical intervention Hematoma related to the nephrostomy occurred in 6 cases (4.4%) but operation was necessary in only 2 of these cases. Overall need for repeat surgery involved only 7 patients (5.2%) during the month following transplantation. One of 2 cases of hematoma operated upon required partial excision of the transplantation kidney due to the presence of an intraparenchymatous arteriovenous fistula. A curious finding was that of the 17 cases developing fistulae most of them had received live donor kidneys (5/15) whereas only 12 occurred in the 120 cadaver kidney transplants. Prevention of fistulae appears to be assisted by spatulation of the ureter rather than by its bevelled section, and the maintenance of a long ureteral loop to avoid traction. It is suggested that certain postoperative urine losses may be the result of a hyper-diuresis, without actual dehiscence of the anastomosis. In 4 patients with a urine output of more than 1.5 litres at the time of transplantation, the kidney proximal to the ureteral ligature became infected, and a second nephrectomy was necessary in 4 cases.

摘要

135例患者(40名女性和95名男性)在肾移植过程中进行了输尿管-输尿管吻合术,使用的器官来自尸体供者(120例)或活体供者(15例)。无论之前是否同时进行过肾切除术,保留肾的输尿管均在移植近端进行连接。结果非常有趣:无死亡病例,无需因泌尿系统并发症切除移植物,也无输尿管吻合口狭窄。108例(80%)无泌尿系统并发症,17例(12.6%)出现尿瘘,其中仅5例需要手术干预。6例(4.4%)发生与肾造瘘相关的血肿,但其中仅2例需要手术。移植后当月总体再次手术需求仅涉及7例患者(5.2%)。2例接受手术治疗的血肿患者中,有1例因存在实质内动静脉瘘而需要部分切除移植肾。一个奇怪的发现是,在17例发生尿瘘的病例中,大多数接受的是活体供者的肾脏(5/15),而在120例尸体肾移植中仅发生12例。输尿管的斜切而非斜面切开似乎有助于预防尿瘘,并且维持长输尿管袢以避免牵拉。提示某些术后尿液丢失可能是由于利尿过多,而不是吻合口实际裂开。4例移植时尿量超过1.5升的患者,输尿管结扎近端的肾脏发生感染,4例均需要再次进行肾切除术。

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