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基于超材料的微波成像传感器的设计与实验验证,用于乳腺癌、肺癌和脑癌的检测。

Design and experimental validation of a metamaterial-based sensor for microwave imaging in breast, lung, and brain cancer detection.

机构信息

Department of Physics, College of Science, University of Raparin, Sulaymaniyah, 46012, Iraq.

Engineering Optimization & Modeling Center, Reykjavik University, 102, Reykjavik, Iceland.

出版信息

Sci Rep. 2024 Jul 13;14(1):16177. doi: 10.1038/s41598-024-67103-9.

DOI:10.1038/s41598-024-67103-9
PMID:39003304
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11246499/
Abstract

This study proposes an innovative geometry of a microstrip sensor for high-resolution microwave imaging (MWI). The main intended application of the sensor is early detection of breast, lung, and brain cancer. The proposed design consists of a microstrip patch antenna fed by a coplanar waveguide with a metamaterial (MTM) layer-based lens implemented on the back side, and an artificial magnetic conductor (AMC) realized on as a separate layer. The analysis of the AMC's permeability and permittivity demonstrate that the structure exhibits negative epsilon (ENG) qualities near the antenna resonance point. In addition, reflectivity, transmittance, and absorption are also studied. The sensor prototype has been manufactures using the FR4 laminate. Excellent electrical and field characteristics of the structure are confirmed through experimental validation. At the resonance frequency of 4.56 GHz, the realized gain reaches 8.5 dBi, with 3.8 dBi gain enhancement contributed by the AMC. The suitability of the presented sensor for detecting brain tumors, lung cancer, and breast cancer has been corroborated through extensive simulation-based experiments performed using the MWI system model, which employs four copies of the proposed sensor, as well as the breast, lung, and brain phantoms. As demonstrated, the directional radiation pattern and enhanced gain of the sensor enable precise tumor size discrimination. The proposed sensor offers competitive performance in comparison the state-of-the-art sensors described in the recent literature, especially with respect to as gain, pattern directivity, and impedance matching, all being critical for MWI.

摘要

本研究提出了一种用于高分辨率微波成象(MWI)的微带传感器的创新几何形状。该传感器的主要应用目的是早期检测乳腺癌、肺癌和脑癌。所提出的设计由微带贴片天线组成,由共面波导馈电,在背面实现基于超材料(MTM)层的透镜,以及实现的人工磁导体(AMC)作为单独的层。对 AMC 的磁导率和介电常数的分析表明,该结构在天线共振点附近表现出负的 epsilon(ENG)特性。此外,还研究了反射率、透射率和吸收率。传感器原型已使用 FR4 层压板制造。通过实验验证确认了结构的出色的电气和场特性。在 4.56GHz 的共振频率下,实现的增益达到 8.5dBi,其中 AMC 贡献了 3.8dBi 的增益增强。通过使用 MWI 系统模型进行的广泛基于仿真的实验,证明了所提出的传感器在检测脑肿瘤、肺癌和乳腺癌方面的适用性,该系统模型使用了四个所提出的传感器以及乳房、肺和脑的体模。结果表明,传感器的定向辐射模式和增强的增益能够实现精确的肿瘤尺寸区分。与最近文献中描述的现有技术传感器相比,所提出的传感器具有竞争力的性能,特别是在增益、模式方向性和阻抗匹配方面,所有这些对于 MWI 都是至关重要的。

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