University of Zimbabwe-Clinical Trials Research Centre, Harare, Zimbabwe.
Women's Global Health Imperative, RTI International, Berkeley, CA, USA.
BMC Public Health. 2024 Jul 15;24(1):1876. doi: 10.1186/s12889-024-19390-0.
Multipurpose prevention technologies (MPTs) are products capable of simultaneously addressing multiple sexual and reproductive health needs such as unwanted pregnancy, STIs including HIV-1, and other reproductive tract infections. MPTs are urgently needed to address the double burden of unplanned pregnancy and HIV. While condoms are currently the only accessible MPTs, they are not solely under a woman's control, and female condoms face limitations due to poor acceptability and high cost.
We conducted a sub-analysis of qualitative data from 39 couples participating in the MTN 045 study to examine the perception of couples on choice and acceptability of a "2 in 1" MPT that combines HIV and pregnancy prevention.
Couples recognized the benefits of MPTs for HIV and pregnancy prevention but perceptions tied to each indication and a novel prevention technology tool raised important concerns relevant to use of future MPTs. In the study, participants' perceptions of MPT use were influenced by pregnancy planning. When the timing was less critical, they prioritized HIV prevention. Misinformation about family planning methods, including MPTs, affected decision-making with potential to hinder uptake of future MPTs. Concerns about side effects, such as weight gain and hormonal imbalances, influenced willingness to use MPTs.
Addressing the myths and misconceptions surrounding the use of contraceptives is crucial in promoting their acceptance and ultimate use. Strategies for addressing the drawbacks women might experience while using a particular product should be in place as new MPTs progress through the development pipeline and approach roll-out.
多用途预防技术(MPTs)是能够同时满足多种性健康和生殖健康需求的产品,例如意外怀孕、性传播感染(包括 HIV-1)和其他生殖道感染。急需 MPTs 来应对意外怀孕和 HIV 的双重负担。虽然避孕套是目前唯一可获得的 MPT,但它们不完全由女性控制,并且由于可接受性差和成本高,女用避孕套面临限制。
我们对参与 MTN 045 研究的 39 对夫妇的定性数据进行了子分析,以检查夫妇对结合 HIV 和妊娠预防的“二合一”MPT 的选择和可接受性的看法。
夫妇认识到 MPTs 预防 HIV 和妊娠的好处,但与每种适应症和新的预防技术工具相关的看法引起了与未来 MPT 使用相关的重要问题。在研究中,参与者对 MPT 使用的看法受到妊娠计划的影响。当时间不那么关键时,他们优先考虑 HIV 预防。对计划生育方法(包括 MPTs)的误解会影响决策,有可能阻碍未来 MPT 的采用。对副作用的担忧,例如体重增加和激素失衡,影响了使用 MPTs 的意愿。
解决围绕使用避孕药具的误解和误解至关重要,有助于促进它们的接受和最终使用。随着新的 MPT 通过开发管道并接近推出,应制定策略来解决女性在使用特定产品时可能遇到的问题。