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抗精神病药物治疗首发精神病后康复的意义:一项定性现象学研究。

Making Sense of Recovery From First Psychosis With Antipsychotic Medication: A Qualitative Phenomenological Study.

机构信息

Department of Psychiatry, Amsterdam University Medical Center, Location Academic Medical Center, Amsterdam, The Netherlands.

Department of Clinical Psychology, University of Amsterdam, Amsterdam, The Netherlands.

出版信息

Schizophr Bull. 2024 Nov 8;50(6):1508-1520. doi: 10.1093/schbul/sbae104.

DOI:10.1093/schbul/sbae104
PMID:39004928
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11548922/
Abstract

BACKGROUND AND HYPOTHESIS

Recovering from a first psychosis is a highly individual process and requires the person to make sense of their experiences. Clinicians, in turn, need to comprehend these first-person perspectives, creating a mutual sense-making dynamic. Antipsychotic medication is a substantial part of psychosis treatment. Providing insight in the lived experience of recovery with antipsychotics could improve the mutual understanding and help bridge the gap between the perspective of the clinician and that of the person recovering from psychosis.

STUDY DESIGN

14 persons in recovery from a first psychosis with the use of antipsychotics were interviewed. Their narratives were analyzed using Interpretative Phenomenological Analysis (IPA).

STUDY RESULTS

Five overarching themes were found, representing important and meaningful experiences in recovering with antipsychotic medication. Theme 1: antipsychotics as external dampening (4 subthemes); Theme 2: shifting of realities; Theme 3: pace of recovery; Theme 4: antipsychotics' influence on identity; and Theme 5: is it truly the antipsychotics?

CONCLUSIONS

Our findings show that recovery from psychosis with antipsychotics is an all-encompassing, multi-faceted, and ambivalent experience. The themes found in this research could inspire clinicians to discuss less obvious aspects of the experience of recovering with antipsychotics. Even more so, paying attention to the first-person perspective could lead to a more thorough understanding and benefit therapeutic relationships.

摘要

背景与假设

从首次精神病发作中恢复是一个高度个体化的过程,需要患者理解自己的经历。反过来,临床医生也需要理解这些第一人称视角,从而形成一种相互理解的动态。抗精神病药物是精神病治疗的重要组成部分。深入了解使用抗精神病药物恢复的亲身经历,可以增进相互理解,有助于缩小临床医生和精神病康复者之间的观点差距。

研究设计

对 14 名正在使用抗精神病药物从首次精神病发作中康复的患者进行了访谈。他们的叙述采用解释性现象学分析(IPA)进行了分析。

研究结果

发现了五个总体主题,代表了使用抗精神病药物康复过程中的重要和有意义的体验。主题 1:抗精神病药物作为外部抑制(4 个子主题);主题 2:现实的转变;主题 3:恢复的速度;主题 4:抗精神病药物对身份的影响;主题 5:真的是抗精神病药物吗?

结论

我们的研究结果表明,使用抗精神病药物从精神病中康复是一个全面的、多方面的、矛盾的体验。本研究中发现的主题可以激发临床医生讨论使用抗精神病药物康复体验中不太明显的方面。更重要的是,关注第一人称视角可以更深入地理解并有益于治疗关系。

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本文引用的文献

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Antipsychotics and Identity: The Adverse Effect No One is Talking About.抗精神病药物与身份认同:一种无人谈及的副作用。
Community Ment Health J. 2025 Feb;61(2):228-233. doi: 10.1007/s10597-024-01255-w. Epub 2024 Mar 1.
2
Self-Disorder in Schizophrenia: A Revised View (1. Comprehensive Review-Dualities of Self- and World-Experience).精神分裂症中的自我紊乱:一种修正观点(1. 全面综述——自我和世界经验的二元性)。
Schizophr Bull. 2024 Mar 7;50(2):460-471. doi: 10.1093/schbul/sbad169.
3
Self-Disorder in Schizophrenia: A Revised View (2. Theoretical Revision-Hyperreflexivity).精神分裂症中的自我障碍:一种修正观点(2. 理论修正——过度反射性)
Schizophr Bull. 2024 Mar 7;50(2):472-483. doi: 10.1093/schbul/sbad170.
4
Personal preferences for treatment and care during and after a First Episode Psychosis: A qualitative study.首发精神病期及康复期的治疗与护理个人偏好:定性研究。
Early Interv Psychiatry. 2024 Jun;18(6):415-424. doi: 10.1111/eip.13477. Epub 2023 Nov 29.
5
Personal narratives and the pursuit of purpose and possibility in psychosis: directions for developing recovery-oriented treatments.个人叙事与精神病中追求目标和可能性:发展以康复为导向的治疗方法的方向。
Expert Rev Neurother. 2023 Jun;23(6):525-534. doi: 10.1080/14737175.2023.2216384. Epub 2023 May 26.
6
Long-Term Outcomes of First-Admission Psychosis: A Naturalistic 21-Year Follow-Up Study of Symptomatic, Functional and Personal Recovery and Their Baseline Predictors.首发精神病的长期结局:一项对症状、功能和个人康复及其基线预测因素的自然随访 21 年研究。
Schizophr Bull. 2022 May 7;48(3):631-642. doi: 10.1093/schbul/sbab145.
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Uncovering the realities of delusional experience in schizophrenia: a qualitative phenomenological study in Belgium.揭示精神分裂症妄想体验的现实:比利时的定性现象学研究。
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Narrative identity in the psychosis spectrum: A systematic review and developmental model.精神病谱系中的叙事身份:系统评价与发展模型。
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