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使用尾套式血压计对尤卡坦小型猪进行无创血压测量。

Non-invasive blood pressure measurement in Yucatan miniature swine using tail cuff sphygmomanometry.

作者信息

Cimini C M, Zambraski E J

出版信息

Lab Anim Sci. 1985 Aug;35(4):412-6.

PMID:3900580
Abstract

A relatively new non-invasive method using a photo-electric flow sensor in non-heated animals, was evaluated for its accuracy in measuring systolic blood pressure (SBP), diastolic blood pressure (DBP) and mean arterial pressure (MAP) in 40-90 Kg normotensive and hypertensive Yucatan miniature swine. Directly measured SBP, DBP and electronically averaged MAP were recorded from chronic arterial catheters simultaneously with indirect pressures, cuff pressure and tail blood flow under various conditions. In all of the tests tail cuff SBP estimation averaged within 5% of directly measured SBP. The correlation of the two methods was significant (r = .95, P less than 0.01). Over a 60 to 202 mmHg range of blood pressure induced pharmacologically or due to DOCA hypertension, the tail cuff SBP was within 4-10% of directly measured SBP. The tail cuff method was also used to determine DBP and MAP. DBP determined from the tail cuff record was found consistently to underestimate the direct measured DBP by approximately 17%. The two methods were correlated (r = .87 P less than 0.01). The measured tail cuff MAP generally underestimated the direct MAP by approximately 5%. The correlation of directly measured MAP and tail cuff methods was significant (r = .72, P less than 0.01). These results indicated that this system may be used to accurately assess blood pressure in miniature swine.

摘要

一种相对较新的、在未加热动物身上使用光电流量传感器的非侵入性方法,在40 - 90千克血压正常和高血压的尤卡坦小型猪中,对其测量收缩压(SBP)、舒张压(DBP)和平均动脉压(MAP)的准确性进行了评估。在各种条件下,从慢性动脉导管直接测量SBP、DBP,并同时用间接测量法记录袖带压力和尾血流量,通过电子方式计算平均动脉压。在所有测试中,尾袖带法估算的SBP平均在直接测量值的5%以内。两种方法的相关性显著(r = 0.95,P < 0.01)。在通过药物诱导或因去氧皮质酮(DOCA)高血压导致的60至202毫米汞柱血压范围内,尾袖带法测量的SBP在直接测量值的4% - 10%以内。尾袖带法也用于测定DBP和MAP。从尾袖带记录中测定的DBP始终比直接测量值低约17%。两种方法具有相关性(r = 0.87,P < 0.01)。测量的尾袖带MAP通常比直接测量值低约5%。直接测量的MAP与尾袖带法的相关性显著(r = 0.72,P < 0.01)。这些结果表明,该系统可用于准确评估小型猪的血压。

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