Wiester M J, Iltis R
J Lab Clin Med. 1976 Feb;87(2):354-61.
A noninvasive method to determine systolic, diastolic, and mean blood pressure values in rhesus monkeys is described and evaluated. Simultaneous measurements of abdonimal aortic and tail-cuff pressures were compared for unanesthetized, anesthetized, hemorrhaged, and methoxamine-treated animals. Data indicated that correlation between direct and indirect methods were highly significant (r greater than or equal to 0.94); the mean differences found between the two measurements were less than or equal to 8 mm. Hg, with the exception of the methoxamine-treated groups. Reliability of the technique was considerably reduced following administration of this drug.
描述并评估了一种用于测定恒河猴收缩压、舒张压和平均血压值的非侵入性方法。对未麻醉、麻醉、出血和用甲氧明处理的动物，同时测量腹部主动脉压和尾袖带压并进行比较。数据表明，直接法和间接法之间的相关性非常显著（r大于或等于0.94）；除甲氧明处理组外，两种测量之间的平均差异小于或等于8毫米汞柱。使用该药物后，该技术的可靠性显著降低。
