1,2-氮杂硼苯的N-官能化
N-Functionalization of 1,2-Azaborines.
作者信息
Lee Hyelee, Alvarado Marisol, Ingram Sarah, Li Bo, Liu Shih-Yuan
机构信息
Department of Chemistry, Boston College, Chestnut Hill, MA 02467-3860, USA.
Accent Therapeutics, Inc., 1050 Waltham Street, Suite 201, Lexington, MA 02421, USA.
出版信息
Synlett. 2023 Nov;34(18):2169-2174. doi: 10.1055/a-2108-9895. Epub 2023 Jul 31.
Abstract
General protocols for the N-functionalization of 1,2-azaborines with C(sp), C(sp), or C(sp) electrophiles are described. The syntheses of a new parental BN isostere of -stilbene and a BN isostere of a lisdexamfetamine derivative were accomplished with the developed methodology.
摘要
描述了用C(sp)、C(sp)或C(sp)亲电试剂对1,2-氮杂硼烷进行N-官能化的通用方案。采用所开发的方法合成了一种新的-二苯乙烯母体BN等排体和一种赖右苯丙胺衍生物的BN等排体。
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