• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

有氧运动与认知训练(ACT)试验中患有遗忘型轻度认知障碍的老年人的心肺适能与认知之间的关系:性别差异

Relations Between Cardiorespiratory Fitness and Cognition in Older Adults With Amnestic Mild Cognitive Impairment From the Aerobic Exercise and Cognitive Training (ACT) Trial: Sex Differences.

作者信息

Yu Fang, Salisbury Dereck, Pituch Keenan A, Lin Feng Vankee

机构信息

University of Minnesota School of Nursing, Minneapolis, Minnesota, United States.

Arizona State University Edson College of Nursing and Health Innovation, Phoenix, Arizona, United States.

出版信息

Arch Rehabil Res Clin Transl. 2024 Apr 17;6(2):100341. doi: 10.1016/j.arrct.2024.100341. eCollection 2024 Jun.

DOI:10.1016/j.arrct.2024.100341
PMID:39006107
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11240017/
Abstract

OBJECTIVE

To examine the associations of cardiorespiratory fitness with executive function, episodic memory, and global cognition and sex differences in these associations in community-dwelling older adults with amnestic mild cognitive impairment.

DESIGN

A cross-sectional study using baseline data from the aerobic exercise and cognitive training (ACT) trial.

SETTING

The ACT trial conducted exercise testing in an exercise laboratory and data collections in a research facility.

PARTICIPANTS

ACT trial participants were recruited through referrals, registries, exhibits, flyers, media, and advertisements and screened for eligibility. To be eligible for this study, ACT enrollees needed complete data on all study variables. Among 146 ACT enrollees, 142 met eligibility for this study (N=142).

INTERVENTIONS

None.

MAIN OUTCOME MEASURES

Cardiorespiratory fitness was measured as peak oxygen consumption (Vo) with a peak cycle-ergometer test, executive function with the EXAMINER, episodic memory with the Brief Visuospatial Memory Test-Revised, and global cognition with Montreal Cognitive Assessment.

RESULTS

The average age of the sample was 73.8±5.8 years with 16.9±2.9 years of education, with 87.3% White, 51.4% men, and 69.7% married. After controlling for covariates, Vo was significantly related to executive function (=.037, standard error [SE]=0.015, =.0154, semipartial [] correlation coefficient=.239) and episodic memory (=.590, SE=0.226, .0102, =.216), but not global cognition (=.074, SE=0.055, .1837, =.125). For men, Vo was significantly associated with executive function (=.063, SE=0.024, =.0099, =.430) and episodic memory (=1.088, SE=0.312, =.0009, =.382).

CONCLUSIONS

Our findings show that Vo was associated with executive function and episodic memory in the overall sample and in men. Future studies can examine the longitudinal relations between cardiorespiratory fitness and cognition.

摘要

目的

探讨社区居住的患有遗忘型轻度认知障碍的老年人中,心肺适能与执行功能、情景记忆和整体认知之间的关联以及这些关联中的性别差异。

设计

一项横断面研究,使用有氧运动与认知训练(ACT)试验的基线数据。

设置

ACT试验在运动实验室进行运动测试,并在研究机构进行数据收集。

参与者

ACT试验参与者通过转诊、登记、展览、传单、媒体和广告招募,并进行资格筛选。要符合本研究的条件,ACT参与者需要有所有研究变量的完整数据。在146名ACT参与者中,142名符合本研究的资格(N = 142)。

干预措施

无。

主要结局指标

通过峰值功率计测试以峰值耗氧量(Vo)测量心肺适能,使用EXAMINER评估执行功能,使用修订版简短视觉空间记忆测试评估情景记忆,使用蒙特利尔认知评估量表评估整体认知。

结果

样本的平均年龄为73.8±5.8岁,受教育年限为16.9±2.9年,其中87.3%为白人,51.4%为男性,69.7%已婚。在控制协变量后,Vo与执行功能显著相关(= 0.037,标准误[SE] = 0.015,= 0.0154,半偏[]相关系数 = 0.239)和情景记忆显著相关(= 0.590,SE = 0.226,= 0.0102,= 0.216),但与整体认知无显著相关性(= 0.074,SE = 0.055,= 0.1837,= 0.125)。对于男性,Vo与执行功能显著相关(= 0.063,SE = 0.024,= 0.0099,= 0.430)和情景记忆显著相关(=

相似文献

1
Relations Between Cardiorespiratory Fitness and Cognition in Older Adults With Amnestic Mild Cognitive Impairment From the Aerobic Exercise and Cognitive Training (ACT) Trial: Sex Differences.有氧运动与认知训练(ACT)试验中患有遗忘型轻度认知障碍的老年人的心肺适能与认知之间的关系:性别差异
Arch Rehabil Res Clin Transl. 2024 Apr 17;6(2):100341. doi: 10.1016/j.arrct.2024.100341. eCollection 2024 Jun.
2
A longitudinal study of cardiorespiratory fitness and cognitive function in healthy older adults.健康老年人心肺适能与认知功能的纵向研究。
J Am Geriatr Soc. 2003 Apr;51(4):459-65. doi: 10.1046/j.1532-5415.2003.51153.x.
3
Efficacy and mechanisms of combined aerobic exercise and cognitive training in mild cognitive impairment: study protocol of the ACT trial.有氧运动与认知训练相结合对轻度认知障碍的疗效及机制:ACT试验研究方案
Trials. 2018 Dec 22;19(1):700. doi: 10.1186/s13063-018-3054-0.
4
Cardiorespiratory Fitness and Cognition: Longitudinal Associations in the FINGER Study.心肺适能与认知:FINGER 研究中的纵向关联。
J Alzheimers Dis. 2019;68(3):961-968. doi: 10.3233/JAD-180897.
5
Neurocognitive Plasticity Is Associated with Cardiorespiratory Fitness Following Physical Exercise in Older Adults with Amnestic Mild Cognitive Impairment.神经认知可塑性与老年遗忘型轻度认知障碍患者进行体力活动后的心肺功能适应性相关。
J Alzheimers Dis. 2021;81(1):91-112. doi: 10.3233/JAD-201429.
6
A Randomized Controlled Trial of High-Intensity Exercise and Executive Functioning in Cognitively Normal Older Adults.一项针对认知正常的老年人群中高强度运动和执行功能的随机对照试验。
Am J Geriatr Psychiatry. 2021 Feb;29(2):129-140. doi: 10.1016/j.jagp.2020.06.015. Epub 2020 Jun 21.
7
One-year aerobic exercise altered cerebral vasomotor reactivity in mild cognitive impairment.一年的有氧运动改变了轻度认知障碍患者的脑血管反应性。
J Appl Physiol (1985). 2021 Jul 1;131(1):119-130. doi: 10.1152/japplphysiol.00158.2021. Epub 2021 May 20.
8
The association between cardiovascular health and cognition in adults with Down syndrome.成年唐氏综合征患者的心血管健康与认知能力的关系。
J Neurodev Disord. 2023 Dec 6;15(1):43. doi: 10.1186/s11689-023-09510-z.
9
Effects of aerobic exercise on mild cognitive impairment: a controlled trial.有氧运动对轻度认知障碍的影响:一项对照试验。
Arch Neurol. 2010 Jan;67(1):71-9. doi: 10.1001/archneurol.2009.307.
10
Cardiorespiratory Fitness Is Associated With Cognitive Performance in Older But Not Younger Adults.心肺适能与老年人而非年轻人的认知表现相关。
J Gerontol B Psychol Sci Soc Sci. 2016 May;71(3):474-82. doi: 10.1093/geronb/gbu167. Epub 2014 Dec 20.

本文引用的文献

1
Cardiorespiratory fitness and risk of Alzheimer's disease and related dementias among American veterans.心肺适能与美国退伍军人中阿尔茨海默病及相关痴呆症的风险。
Alzheimers Dement. 2023 Oct;19(10):4325-4334. doi: 10.1002/alz.12998. Epub 2023 Mar 22.
2
Sex Differences in VO and the Impact on Endurance-Exercise Performance.VO 中的性别差异及其对耐力运动表现的影响。
Int J Environ Res Public Health. 2022 Apr 19;19(9):4946. doi: 10.3390/ijerph19094946.
3
Risk Factors Associated With Alzheimer Disease and Related Dementias by Sex and Race and Ethnicity in the US.美国按性别、种族和族裔划分的与阿尔茨海默病及相关痴呆症相关的风险因素。
JAMA Neurol. 2022 Jun 1;79(6):584-591. doi: 10.1001/jamaneurol.2022.0976.
4
Five-year changes in objectively measured cardiorespiratory fitness, physical activity, and sedentary time in mid-to-late adulthood.中年后期客观测量的心肺健康、身体活动和久坐时间的 5 年变化。
Appl Physiol Nutr Metab. 2022 Feb;47(2):206-209. doi: 10.1139/apnm-2021-0500. Epub 2021 Nov 25.
5
Cardiorespiratory fitness mitigates brain atrophy and cognitive decline in adults at risk for Alzheimer's disease.心肺适能可减轻有患阿尔茨海默病风险的成年人的脑萎缩和认知衰退。
Alzheimers Dement (Amst). 2021 Jul 12;13(1):e12212. doi: 10.1002/dad2.12212. eCollection 2021.
6
Neurocognitive Plasticity Is Associated with Cardiorespiratory Fitness Following Physical Exercise in Older Adults with Amnestic Mild Cognitive Impairment.神经认知可塑性与老年遗忘型轻度认知障碍患者进行体力活动后的心肺功能适应性相关。
J Alzheimers Dis. 2021;81(1):91-112. doi: 10.3233/JAD-201429.
7
Inter-individual differences in the responses to aerobic exercise in Alzheimer's disease: Findings from the FIT-AD trial.阿尔茨海默病患者对有氧运动反应的个体间差异:来自 FIT-AD 试验的结果。
J Sport Health Sci. 2021 Jan;10(1):65-72. doi: 10.1016/j.jshs.2020.05.007. Epub 2020 Jun 4.
8
Establishing Reference Cardiorespiratory Fitness Parameters in Alzheimer's Disease.建立阿尔茨海默病患者的参考心肺适能参数。
Sports Med Int Open. 2020 Jan 30;4(1):E1-E7. doi: 10.1055/a-1089-4957. eCollection 2020 Jan.
9
Sex and Gender Differences in Alzheimer's Disease Dementia.阿尔茨海默病性痴呆中的性别差异
Psychiatr Times. 2018 Nov;35(11):14-17. Epub 2018 Dec 30.
10
Efficacy and mechanisms of combined aerobic exercise and cognitive training in mild cognitive impairment: study protocol of the ACT trial.有氧运动与认知训练相结合对轻度认知障碍的疗效及机制:ACT试验研究方案
Trials. 2018 Dec 22;19(1):700. doi: 10.1186/s13063-018-3054-0.